I-Vinca Rosea Extract Vincristine
I-Vinca Rosea Extract I-Vincristine ibhekisa kwi-compound yamayeza i-Vincristine, ephuma kwisityalo i-periwinkle (i-Vinca rosea), eyaziwa ngokuba yi-Catharanthus roseus, amehlo aqaqambileyo, i-Cape periwinkle, isityalo samangcwaba, i-Madagascar periwinkle, i-old maid, i-pink periwinkle, i-rose periwinkle, luhlobo lwesityalo esihlala sihleli kusapho lwe-Apocynaceae.
I-Vincristine yi-alkaloid yendalo kwaye isetyenziswa njengeyeza le-chemotherapy ukunyanga iintlobo ezahlukeneyo zomhlaza, kubandakanya i-leukemia, i-lymphoma, kunye neethumba eziqinileyo. Isebenza ngokuphazamisa ukukhula kweeseli zomhlaza.
| Izithako eziphambili ezisebenzayo ngesiTshayina | Igama lesiNgesi | Inombolo ye-CAS | Ubunzima beMolekyuli | Ifomula yeMolekyuli |
| 长春胺 | I-Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | I-Anhydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | IStrictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | I-Tetrahydroalstonine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | I-Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | I-Vinorelbine | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | UVincristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | I-Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | I-Catharanthine Sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | I-Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | IVinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | ICatharanthine | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | I-Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | I-Vinblastine Sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β-谷甾醇 | i-β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | I-Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | I-asidi ye-oleanolic | 508-02-1 | 456.7 | C30H48O3 |
| IINKCUKACHA ZEMVELISO | ||
| Igama lemveliso: | I-Vinca rosea ethe ngqo | |
| Igama lezityalo: | I-Catharanthus roseus (L.) | |
| Inxalenye yesityalo | Intyatyambo | |
| Ilizwe lemveli: | iTshayina | |
| IZINTO ZOHLALUTYO | IINKCUKACHA | INDLELA YOVAVANYO |
| Inkangeleko | Umgubo ocolekileyo | I-Organoleptic |
| Umbala | Umgubo ocolekileyo omdaka | Imbonakalo |
| Ivumba kunye neNcasa | Uphawu | I-Organoleptic |
| Ukuchongwa | Ifana nesampulu ye-RS | I-HPTLC |
| Isilinganiselo seSicatshulwa | 4:1~20:1; UVincristine 98%min | |
| Uhlalutyo lwesihluzo | I-100% ukuya kwi-80 mesh | I-USP39 <786> |
| Ilahleko yokomisa | ≤ 5.0% | I-Euro.Ph.9.0 [2.5.12] |
| Uthuthu olupheleleyo | ≤ 5.0% | I-Euro.Ph.9.0 [2.4.16] |
| Inkokeli (Pb) | ≤ 3.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Arsenic (As) | ≤ 1.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Cadmium (i-Cd) | ≤ 1.0 mg/kg | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| I-Mercury (Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | I-Eur.Ph.9.0<2.2.58>ICP-MS |
| Intsimbi enzima | ≤ 10.0 mg/kg | I-Euro.Ph.9.0<2.4.8> |
| Intsalela yeSolvents | Vumelana ne-Eur.ph. 9.0 <5,4 > kunye ne-EC European Directive 2009/32 | I-Euro.Ph.9.0<2.4.24> |
| Iintsalela zeZibulali-zinambuzane | Imigaqo yokuhambelana (EC) No. 396/2005 kuquka izihlomelo kunye nohlaziyo olulandelelanayo Ubhaliso luka-2008/839/CE | I-Chromatography yeGesi |
| Iibhaktheriya ze-Aerobic (TAMC) | ≤10000 cfu/g | I-USP39 <61> |
| Imvubelo/Iimolds (TAMC) | ≤1000 cfu/g | I-USP39 <61> |
| I-Escherichia coli: | Akukho kwi-1g | I-USP39 <62> |
| I-Salmonella spp: | Akukho kwi-25g | I-USP39 <62> |
| I-Staphylococcus aureus: isifo sephepha | Akukho kwi-1g | |
| I-Listeria Monocytogenens | Akukho kwi-25g | |
| Ii-Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | I-USP39 <62> |
| Ii-Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | I-USP39 <62> |
Iimpawu zemveliso yeVinca Rosea Extract Vincristine zingaquka:
Ubunyulu obuphezulu:Iimveliso zeVincristine zihlala zicocekile kakhulu kwaye zihambelana nemigangatho engqongqo yokwenziwa kwamayeza ukuqinisekisa ubunyulu kunye nozinzo lwamayeza.
Ukulandeleka komthombo:I-Vincristine idla ngokutsalwa kwisityalo iCatharanthus roseus. Inkqubo yayo yokuvelisa ilandelelwa kwaye ihambelana nemigaqo yokuqokelelwa kunye nokuveliswa kwezinto zonyango lwezityalo.
Uzinzo lweekhemikhali:Njengekhompawundi ye-alkaloid, i-vincristine inamandla afanelekileyo eekhemikhali kwaye ifanelekile kwimveliso yamayeza kunye nokugcinwa ixesha elide.
Umsebenzi wokulwa nomhlaza:Njengeyeza lokulwa nomhlaza, i-vincristine inomsebenzi wokuthintela ukukhula nokusasazeka kweeseli zomhlaza kwaye ifanelekile kunyango lwee-cancer ezahlukeneyo.
Ukuqinisekiswa kweklinikhi:I-Vincristine iqinisekisiwe ngokwezonyango kwaye isetyenziswa kakhulu kwezonyango, ngenkxaso ethembekileyo yedatha yezonyango kunye neziphumo zonyango.
Ezi mpawu zemveliso zibonisa umgangatho, umsebenzi, kunye nexabiso leklinikhi le-vincristine njengeyeza elibalulekileyo lokulwa nomhlaza.
I-Vinca Rosea Extract I-Vincristine yaziwa kakhulu ngokusetyenziswa kwayo kweyeza kunyango lomhlaza kwaye ayiqhelekanga ukunxulunyaniswa neenzuzo ezithe ngqo zempilo zokusetyenziswa ngokubanzi ngabathengi. I-Vincristine, ethathwe kwisityalo se-Vinca rosea, liyeza elinamandla le-chemotherapy elisetyenziselwa ukunyanga iintlobo ezahlukeneyo zomhlaza, kubandakanya i-leukemia, i-lymphoma, kunye neethumba eziqinileyo. Isebenza ngokuphazamisa ukukhula kweeseli zomhlaza.
Kubalulekile ukuqaphela ukuba iVincristine liyeza elinikwa ngugqirha elilawulwa ziingcali zempilo, kwaye ukusetyenziswa kwalo kunxulunyaniswa nemiphumo emibi kunye neengozi ezinokubakho. Ke ngoko, alisoloko lithengiswa okanye lisetyenziswa ngenxa yeenzuzo zalo zempilo ngaphandle kweendawo zonyango.
Iinkcukacha ezipheleleyo zeVinca Rosea Extract Vincristine ziquka:
Unyango lomhlaza:I-Vincristine isetyenziswa kakhulu kunyango lweentlobo ezahlukeneyo zomhlaza, kubandakanya i-leukemia, i-lymphoma, kunye neethumba eziqinileyo. Inikwa njengenxalenye yeenkqubo ze-chemotherapy ukuthintela ukukhula kweeseli zomhlaza.
Uphando lweMithi:Esi sicatshulwa sisetyenziswa kuphando lwamayeza ukuphuhlisa unyango olutsha lomhlaza kunye nophando lwendlela esebenza ngayo.
Ikhemistri Yezonyango:I-Vincristine isebenza njengekhompawundi exabisekileyo kwicandelo lekhemistri yezonyango, inegalelo ekuphuhlisweni kwamayeza amatsha kunye neearhente zonyango.
I-Biotechnology:Isicatshulwa singasetyenziswa kwizicelo ze-biotechnology, njengokuvelisa iindlela zokulwa nomhlaza kunye neenkqubo zokuhambisa amayeza.
Uvavanyo lwezonyango:IVincristine ibandakanyeka kuvavanyo lweklinikhi ukuze ihlolisise ukusebenza kwayo ekunyangeni iintlobo ezahlukeneyo zomhlaza kunye nokuphanda ukusetyenziswa kwayo kwezinye iimeko zonyango.
Ukwenziwa Kwamayeza:Esi sicatshulwa sisetyenziswa ekwenzeni iimveliso zamayeza, kuquka izisombululo ezifakwa kwi-injection kunye nezinye iindlela zokulinganisa unyango lomhlaza.
Ezi zicelo zibonisa ukusetyenziswa okuhlukeneyo kweVinca Rosea Extract Vincristine kunyango lomhlaza, uphando lwamayeza, kunye nophuhliso lwamayeza.
I-Vincristine liyeza elinamandla le-chemotherapy, kwaye ukusetyenziswa kwayo kunokunxulunyaniswa neziphumo ebezingalindelekanga ezininzi. Ezinye zeziphumo ebezingalindelekanga ze-Vincristine powder zingabandakanya:
Ubuthi be-neurotoxic:I-Vincristine inokubangela umonakalo kwinkqubo yemithambo-luvo ejikeleze umzimba, nto leyo ekhokelela kwiimpawu ezinje ngokuba ndindisholo, ukurhawuzelelwa, kunye nobuthathaka kwimilenze.
Iziphumo zesisu:Iziphumo eziqhelekileyo zesisu zingabandakanya isicaphucaphu, ukuhlanza, ukuqhina, kunye nentlungu yesisu.
Ukuncitshiswa kweBone Marrow:I-Vincristine inokucinezela umongo wethambo, nto leyo ekhokelela ekunciphiseni ukuveliswa kweeseli zegazi, nto leyo enokubangela i-anemia, ukwanda kokusuleleka zizifo, kunye nokuthambekela kokopha.
Ukulahleka Kweenwele:Abanye abantu banokuphulukana neenwele okanye banciphe ngenxa yonyango lweVincristine.
Intlungu Yemihlathi:I-Vincristine inokubangela uhlobo oluthile lwentlungu eyaziwa ngokuba yi-"vincristine-induced neuropathy-acute-onset," ebonakaliswa ziintlungu zomhlathi kunye nobunzima bokuginya.
Ezinye Iziphumo Ezinokubakho:Ezinye iziphumo ebezingalindelekanga zingabandakanya ubuthathaka bemisipha, utshintsho kuxinzelelo lwegazi, kunye neempendulo ze-allergy.
Kubalulekile ukuqaphela ukuba olu luhlu lungasentla aluphelelanga, kwaye iingcali zonyango kufuneka zijonge ngokusondeleyo abantu abafumana iVincristine ukuze babone naziphi na iziphumo ebezingalindelekanga. Iziphumo ebezingalindelekanga ezithile kunye nobunzima bazo zinokwahluka kumntu nomntu. Izigulana kufuneka zixoxe ngeziphumo ebezingalindelekanga kunye neenkxalabo ezinokubakho nomboneleli wezempilo ngaphambi kokuba ziqale unyango lweVincristine.
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Ukupakisha
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* Ubunzima obupheleleyo: 25kgs/igubu, Ubunzima obupheleleyo: 28kgs/igubu
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