I-Rotundine Powder enyulu(l-tetrahydropalmatine,l-THP)
I-Rotundine, eyaziwa ngokuba yi-l-tetrahydropalmatine (l-THP), i-compound eneempawu ze-pharmacological ezichaphazela inkqubo ye-nervous central kunye ne-cardiovascular system. Kuye kwaxelwa ukuba kune-analgesic, sedative, hypnotic, kunye nemiphumo ye-anxiolytic. Ukongezelela, kuye kwaboniswa ukuba kuneempembelelo zokukhusela kwi-cerebral kunye ne-myocardial ischemia-reperfusion injury. I-Rotundine yaziwa ngokuba namandla ayo okubuyisela umva ukunganyangeki kweziyobisi kwiiseli zomhlaza kunye neempawu zayo zokuthintela umjelo we-calcium.
Inokufumaneka kwii-tubers ze-Stephania tetrandra kunye ne-Corydalis yanhusuo, okanye ngeendlela ze-chemical synthesis. Idityaniswe ukusuka kwi-tetrahydropalmatine ngokunciphisa, ukuqhekeka, kunye nokuphendula kwe-alkalization. I-tetrahydropalmatine ene-iodine inokuveliswa kwi-tetrahydropalmatine ngokusebenzisa i-alkalization kunye ne-oxidation ukwenzela ukuhlanganiswa okuphindaphindiweyo.
Kwi-pharmacokinetics, i-Rotundine ifakwe kakuhle emva kokulawulwa komlomo kwaye isasazwa ngokuyinhloko kwizicubu ze-adipose, ilandelwa yimiphunga, isibindi kunye nezintso. Ikakhulu ikhutshwa ngeentso. Uphononongo kwiimpuku kunye nemivundla lubonise ukuba i-Rotundine inokungena kwisithintelo segazi-ingqondo kwaye ingene kwizicubu zobuchopho, kunye noxinzelelo lwengqondo olungaphantsi koxinzelelo lwegazi emva kweeyure ze-2.
Ngeziphumo ezibi, i-Rotundine inokubangela ukozela, isiyezi, ukudinwa, isicaphucaphu, kunye nomothuko ngamanye amaxesha. Izilumkiso zibandakanya ukuphepha ukusetyenziswa kwabasetyhini abakhulelweyo nabancancisayo, ukuqaphela amandla okunyamezela kunye nokusetyenziswa kwexesha elide, kunye nokusebenzisa isilumkiso xa usebenzisana ne-central nervous system depressants, kunye nohlengahlengiso olufanelekileyo lwedosi xa kuyimfuneko.
Isishwankathelo, i-Rotundine yikhompawundi eneziphumo ezahlukeneyo zekhemesti, kwaye iipropathi zayo ziyenza ibe ngumxholo womdla kuphando olwahlukeneyo, kubandakanya nolawulo lweentlungu, impilo yentliziyo, kunye nonyango lomhlaza. Ngolwazi oluthe vetshe qhagamshelanagrace@biowaycn.com.
Ukuphelisa iintlungu:I-Rotundine ibonakaliswe ukuba ineempawu ze-analgesic, eyenza ukuba iphumelele ekunciphiseni intlungu kunye nokukhathazeka.
Iziphumo zokuchasa ukudumba:I-Rotundine ibonise iipropati ezichasayo, ezinokunceda ukunciphisa ukuvuvukala kunye neempawu ezinxulumene nazo.
Ukuphumla kunye ne-sedation:I-Rotundine isetyenziselwa ukukhuthaza ukuphumla kunye ne-sedation, okwenza kube luncedo ekulawuleni uxinzelelo kunye noxinzelelo.
Umsebenzi we-Antioxidant:I-Rotundine ifunyenwe ibonisa iziphumo ze-antioxidant, ezinokunceda ukukhusela iiseli kumonakalo obangelwa yi-radicals yamahhala.
Unyango olunokubakho:Olunye uphando lucebisa ukuba i-Rotundine inokuba namandla okulawula umlutha kunye neempawu zokurhoxisa, ngakumbi ukuxhomekeka kwe-opioid.
Iinzuzo zesisu:I-Rotundine ifundelwe amandla ayo okunciphisa imiba yesisu, njenge-spasms kunye nokungahambi kakuhle.
| Uhlalutyo | Inkcazo |
| Isivavanyi | Tetrahydropalmatine ≥98% |
| Imbonakalo | Umgubo omthubi okhanyayo ukuya kwiPowder emhlophe |
| Uthuthu | ≤0.5% |
| Ukufuma | ≤5.0% |
| Amayeza okubulala izinambuzane | Ibi |
| Iintsimbi ezinzima | ≤10ppm |
| Pb | ≤2.0ppm |
| As | ≤2.0ppm |
| Ivumba | Uphawu |
| Ubungakanani besuntswana | 100% ukuya kwi-80 mesh |
| IMicrobiological : | |
| Iyonke yeebhaktheriya | ≤1000cfu/g |
| Iifungus | ≤100cfu/g |
| Salmgosella | Ibi |
| Coli | Ibi |
I-Rotundine inezicelo kumashishini amaninzi, kuquka:
Umzi mveliso wamachiza:I-Rotundine isetyenziswe kwishishini lamachiza ngenxa ye-analgesic, i-sedative, kunye ne-anxiolytic properties. Inokufakwa kumayeza okulawula iintlungu kunye nokuthomalalisa ixhala.
Ukhathalelo lwempilo kunye nempilo:Ngenxa yeenzuzo zayo zempilo ezixeliweyo, iRotundine inokusetyenziswa kukhathalelo lwempilo kunye neemveliso zempilo ezijolise ekukhuthazeni ukuphumla nokulawula iintlungu.
Uphando nophuhliso:I-Rotundine inomdla kuphando kunye neenzame zophuhliso ezijolise kwimpilo ye-cardiovascular, unyango lomhlaza, kunye neemeko ze-neurological ngenxa yeziphumo ezichazwe kwezi nkqubo.
Nutraceuticals:Kukho amandla okufakwa kwe-Rotundine kwiimveliso ze-nutraceutical ezenzelwe ukuxhasa impilo yonke kunye nokuphila kakuhle.
Kubalulekile ukuqaphela ukuba izicelo ezithile ze-Rotundine zinokwahluka ngokusekelwe kwiimvume ezilawulayo kunye nophando oluqhubekayo kwishishini ngalinye.
Iimveliso zethu zenziwa kusetyenziswa amanyathelo angqongqo olawulo lomgangatho kwaye zithobela imigangatho ephezulu yeenkqubo zemveliso. Sibeka phambili ukhuseleko kunye nomgangatho wemveliso yethu, siqinisekisa ukuba iyahlangabezana neemfuno zolawulo kunye neziqinisekiso zeshishini. Oku kuzibophelela kumgangatho kujolise ekusekeni intembeko kunye nokuzithemba ekuthembekeni kwemveliso yethu. Inkqubo yemveliso jikelele ngolu hlobo lulandelayo:
Ugcino:Gcina kwindawo epholileyo, eyomileyo, necocekileyo, Khusela kubufuma kunye nokukhanya okuthe ngqo.
Umqulu omninzi:20~25kg/igubu.
Ixesha lokukhokhela:Iintsuku ezisi-7 emva kweodolo yakho.
Beka ubomi kwishelufa:iminyaka eyi-2.
NONEIinkcukacha ezilungiselelweyo zinokufezekiswa.
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