I-Corydalis Extract Tetrahydropalmatine (dl-THP)

Igama lemveliso:Tetrahydropalmatine
Inombolo yeCAS. :6024-85-7
Ifomula yemolekyuli:C21H26NO4
Inkcazo:I-Tetrahydropalmatine ≥ 98% HPLC
Imbonakalo:Umthubi okhanyayo ukuya kumgubo wekristale omhlophe, ongenavumba, incasa ekrakra kancinane
Uphawu Oluphambili:Impembelelo ye-Analgesic enomlutha omncinci


Iinkcukacha zeMveliso

Iithegi zeMveliso

Intshayelelo yeMveliso

I-Tetrahydropalmatine (THP), eyaziwa ngokuba yi-dl-THP, i-Corydalin hydrochloride, okanye i-Corydalin Tube Extract, i-compound ehlelwe njenge-alkaloid ye-isoquinoline. Itsalwa kwi-tuber yemifuno yaseTshayina iCorydalis yanhusuo. I-THP yinto engenambala okanye emthubi yekristale ephaphathekileyo enencasa ekrakra kancinane kunye nendawo yokunyibilika eyi-147-149°C. Ayinyibiliki emanzini kodwa inyibilika kakhulu kwi-ether, ichloroform, kunye ne-ethanol. I-hydrochloride yayo kunye neetyuwa zesulfate zinyibilika emanzini.
I-THP iye yafundelwa iziphumo ezahlukeneyo ze-pharmacological, kubandakanywa i-analgesic, i-anesthetic, i-neuroprotective, i-antiplatelet aggregation, i-antiulcer, i-antitumor, kunye ne-anti-addiction properties. Kukholelwa ukuba isebenzise iziphumo zayo ze-analgesic ngokumodareyitha umsebenzi we-dopamine receptor ephakathi kwaye ibonise amandla okukhusela i-neurons kukulimala kwe-ischemic. Ukongeza, i-THP ibonise iziphumo ze-antiplatelet aggregation kwaye iphandiwe ngokukwazi kwayo ukunyanga izilonda, ukuthintela ukukhula kweeseli zethumba, kunye nokunceda ekukhotyokisweni kweziyobisi.
Ngokubanzi, i-Tetrahydropalmatine (dl-THP) iyikhompawundi eneempawu ezahlukeneyo ze-pharmacological kwaye ibe ngumxholo wophando olubanzi malunga nezicelo zonyango ezinokubakho. Ngolwazi oluthe vetshe qhagamshelanagrace@biowaycn.com.

Uphawu

Nazi iimpawu zemveliso yeTetrahydropalmatine (THP) kunye neenzuzo zabo zempilo:
1. Iinkcazelo ngeempawu zokuthomalalisa iintlungu:I-THP ibonisa iziphumo ze-analgesic ngokumodareyitha umbindi we-dopamine receptor umsebenzi, ukubonelela ngesiqabu seentlungu ngaphandle kokubakho okubonakalayo okukhobokisayo.
2. Iimpembelelo zeNeuroprotective:I-THP ibonise amandla okukhusela i-neurons kwingozi ye-ischemic, ukunciphisa i-neuronal apoptosis, kunye nokunciphisa amanqanaba e-glutamate kwingqondo, enokuthi ibe negalelo kwiipropati zayo ze-neuroprotective.
3. IAntiplatelet Aggregation:I-THP ifunyenwe ukuba inqanda ukuhlanganiswa kweplatelet, okunokunciphisa umngcipheko wokwakheka kwehlwili legazi kunye neziganeko ezinxulumene ne-cardiovascular.
4. Inkxaso yeMpilo yeGastric:I-THP ibonise iziphumo ezichasayo zezilonda kwaye inokunceda ekunciphiseni ukukhuselwa kwe-asidi yesisu, inika isiqabu kwizilonda zesisu kunye neemeko ezinxulumene nazo.
5. Umsebenzi onokwenzeka we-Antitumor:I-THP ibonise iziphumo ze-cytotoxic kwiiseli zethumba, iphakamisa indima enokuthi ithintele ukukhula kwethumba.
6. IiPropathi ezichasene nokuSetyenzwa:I-THP ifundelwe amandla ayo okunciphisa iimpawu zokurhoxa ezinxulumene ne-opioid kunye ne-stimulant addiction, inikezela ngesithembiso kunyango lokulutha kunye nokuthintela ukuphinda ubuyele.
Ezi mpawu zibalaselisa iinzuzo ezahlukeneyo zempilo kunye nezicelo ezinokubakho zonyango zeTetrahydropalmatine (THP).

Inkcazo yezityalo

I-Tetrahydropydalin (dl-THP) iyingxenye ye-alkaloids ye-isoquinoline kwaye i-alkaloid, ngokukodwa kwi-genus Corydalis lucidum (Yan Hu Suo), kodwa nakwezinye izityalo ezifana ne-Stephania rotunda. Ezi zityalo zisetyenziselwa amayeza esintu aseTshayina.I-Corydalis sisityalo esihlala ixesha elide, esine-10 ukuya kwi-20 cm ubude, kunye ne-tubers spherical. Iziqu zayo ezingaphezulu komhlaba zimfutshane kwaye zibhityile, zinezikali ezingaphezulu kwesiseko. Amagqabi e-Basal kunye namaqabunga e-cauline afana nesimo, kunye neziqu; amagqabi e-cauline ayatshintshana, ane-2 kunye ne-3 yamagqabi adibeneyo. Igqabi lesibini lidla ngokuqhekeka ngokungaphelelanga kwaye ligobe ngokunzulu. Amagqabi amancinci a-oblong, oval, okanye oval. Umgca, malunga ne-2 cm ubude, kunye ne-pex ebukhali okanye ebukhali kunye neencam ezicocekileyo. I-inflorescence yayo imile okwe-raceme, inamagqabi esiphelo okanye achaseneyo; iibracts zibanzi lanceolate; iintyatyambo zibomvu-mfusa kwaye zikhula ngokuthe tye kwiipedicels ezibhityileyo, ezimalunga ne-6 mm ubude; i-calyx iyawa kwangoko; iipetali ziyi-4 kwaye i-whorls yangaphandle yi-2 Amacandelo makhudlwana kancinane, kunye ne-pink edges kunye ne-bluish-purple centre. Kukho icandelo elinye elingasentla, kwaye umsila udlulela kwi-spur ende. Ubude be-spur bubalelwa kwisiqingatha sobude bubonke. Amacandelo angaphakathi ama-2 ancinci kunamacandelo ama-2 angaphandle. Isiphelo esiphezulu sibomvu-mfusa kwaye siphilisiwe, kwaye icandelo elisezantsi lipinki; I-stamens yi-6, kwaye i-filaments idityaniswe kwii-bundle ezimbini, nganye ine-anthers ezi-3; i-ovary i-flat-cylindrical, isitayela sifutshane kwaye sincinci, kwaye i-stigma yi-2, njengebhabhathane elincinci. Isiqhamo sawo yi-capsule. I-Corydalis iveliswa ikakhulu ezintabeni okanye kumathafa engca. Iindawo eziphambili zokuvelisa ziquka iZhejiang, iHebei, iShandong, iJiangsu, nezinye iindawo.

Inkcazo

Uhlalutyo Inkcazo
Isivavanyi Tetrahydropalmatine ≥98%
Imbonakalo Umgubo omthubi okhanyayo ukuya kwiPowder emhlophe
Uthuthu ≤0.5%
Ukufuma ≤5.0%
Amayeza okubulala izinambuzane Ibi
Iintsimbi ezinzima ≤10ppm
Pb ≤2.0ppm
As ≤2.0ppm
Ivumba Uphawu
Ubungakanani besuntswana 100% ukuya kwi-80 mesh
IMicrobiological :  
Iyonke yeebhaktheriya ≤1000cfu/g
Iifungus ≤100cfu/g
Salmgosella Ibi
Coli Ibi

 

Isicelo

Nanga amashishini osetyenziso lwemveliso yeTetrahydropalmatine (THP):
1. Amachiza:I-THP isetyenziswa kwishishini lamachiza ekuphuhliseni amayeza okulawula iintlungu kunye neziyobisi ze-neuroprotective.
2. Nutraceuticals:I-THP isetyenziswa kwishishini le-nutraceutical ukwenza izongezo ezijolise ekupheliseni iintlungu kunye nenkxaso yempilo yesisu.
3. I-Biotechnology:I-THP ifumana izicelo kwi-biotechnology yophando kunyango lwe-antiplatelet kunye nezinto ezinokubakho zonyango lomhlaza.
4. Ukhathalelo lwempilo:I-THP ibandakanyiwe kwiimveliso zokhathalelo lwempilo ukulawula ukukhotyokiswa kunye neempawu zokurhoxa ezinxulumene ne-opioid kunye nokusetyenziswa okuvuselelayo.
5. Izinto zokuthambisa:I-THP iphononongwa kwi-cosmeceuticals kwimpilo yolusu enokubakho kunye nezicelo zokuchasa ukudumba.
La mashishini abonisa usetyenziso oluhlukeneyo lweTetrahydropalmatine (THP) kuphuhliso lwemveliso eyahlukeneyo kunye neemeko zophando.

Iinkcukacha zeMveliso

Iimveliso zethu zenziwa kusetyenziswa amanyathelo angqongqo olawulo lomgangatho kwaye zithobela imigangatho ephezulu yeenkqubo zemveliso. Sibeka phambili ukhuseleko kunye nomgangatho wemveliso yethu, siqinisekisa ukuba iyahlangabezana neemfuno zolawulo kunye neziqinisekiso zeshishini. Oku kuzibophelela kumgangatho kujolise ekusekeni intembeko kunye nokuzithemba ekuthembekeni kwemveliso yethu. Inkqubo yemveliso jikelele ngolu hlobo lulandelayo:

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