I-Corydalis ikhuphe i-tetrarahdropatine (i-DL-th)
I-Tetrarahydropatine (i-STP), ekwabizwa ngokuba yi-DL-Thp, iCorydalin Hydrochloride, okanye i-corydalin tube ikhutshiwe njengesonquinelidi. Ikhutshwe kumngxunya we-turb ye-Chinese Corrydalis yanhusuo. I-Thp yinto engenamibala okanye i-ryty etyheli ye-crystalline enengca encinci kunye nendawo yokunyibilika ye-147-169 ° C. Kuyinto enganyibilikiyo emanzini kodwa inyibilika kakhulu kwi-ether, chloroform, ne-ethanol. I-hydrochloride ye-hydrochloride kunye ne-sulfate yazo inyibilika emanzini.
I-Thp ifundwe ngemiphumo eyahlukeneyo ye-pharmacolocal, kubandakanya i-analgetic, i-anesthetic, i-neuroproprocective, i-antipeletlet, i-antiulcer, i-antitor, i-antitorum, kunye neePropathi zeSikhoboka. Kukholelwa ukuba ikhuphe imiphumo ye-analgesic yayo ngemodyuli ye-Dousppine Refcine Appler Appler kwaye ibonakalise amandla ekukhuseleni ii-neurons ukusuka kwi-ischemic monakalo. Ukongeza, i-TIP ibonakalise iziphumo zokuhlanganisana i-antipalet kwaye iphandwe ngenxa yokuphatha i-ilcers, ethintelayo ukukhula kwe-tumoor, kunye nokunceda kwikhoboka leziyobisi.
Ngokubanzi, i-tetrarahydropatine (i-DL-th) yinxalenye yepropathi eyahlukeneyo ye-farmes kwaye ibingumxholo wophando olubanzi kwizicelo zayo zonyango ezinokubakho. Ngolwazi oluthe kratyagrace@biowaycn.com.
Nazi iimpawu zemveliso zeTetrarahdroPatine (i-STP) kunye nezibonelelo zazo zempilo:
I-1. I-Analgeric Propathities:I-Thp ibonakalisa iziphumo ze-Analgesic ngemodyuli yeModyprine Dogamine Doptor, ibonelela ngoncedo lwentlungu ngaphandle kokufumana amandla afanelekileyo.
I-2. Iziphumo ze-neuroproupective:I-Thp ibonakalisile ukukhusela ii-neurons kwi-i-Ischemic Moures, ukunciphisa i-Apopptoal Apoptosis, kunye nokuthoba amanqanaba e-glutamate kwingqondo, enokuba negalelo kwizinto zayo ze-neuroproprocetive.
I-3. I-Antipalet yothintelo:I-Thp ifunyenwe i-Thibitor ethintele iplanethi, inokuthi inciphise umngcipheko wokuqulunqwa kwegazi kunye neziganeko zentliziyo ezinxulumene noko.
I-4. Inkxaso yeZenzo zaseGastric:I-STP ibonakalise iziphumo ze-anti-umlt kwaye inokunceda ekunciphiseni ukufihlakala kwe-gestric acid, ukubonelela ngoncedo lwee-ilcers ze-gestric kunye neemeko ezinxulumene noko.
5. Umsebenzi onokubakho we-antitory:I-Thp ibonakalise ukuba neziphumo ze-cytotovity kwiiseli ze-tumor, iphakamisa indima enokubakho kwindima yokukhula kwethusi.
I-6. Iipropathi zesalathiso sokulwa i-Anti -int:I-Thp ifundwe ngenxa yokunciphisa iimpawu zokurhoxa ezinxulumene ne-operid kunye nolutho, ecela isithembiso ngonyango lwelikhobokayo kunye nokuthintela kwakhona.
Ezi mpawu zibonisa izibonelelo ezahlukeneyo zezempilo kunye nokusetyenziswa kwezicelo ezinokubakho zeTetrarahdropatine (i-STP).
I-Tetrarahydropydalin (i-DL-th) yesonquineline alkaloid kwaye iyi-alkaloid, ikakhulu kwi-genus corydalis lucido (yan hu su Steanda. Ezi zityalo zinokusetyenziswa ngokwesiko kunyango lwe-herbal.I-Corydalis sisityalo esingakwaziyo i-hernaceous, i-10 ukuya kwi-20 cm ubude, kunye neetyhubhu ze-slor. Iimpuku zayo ezingentla zimfutshane kwaye zithambele, kunye nesikali ngaphezulu kwesiseko. Amagqabi asisiki kunye namagqabi amapheli ayafana nakwimo, kunye neziqu; Amagqabi e-cauline ayodwa, anamagqabi ama-2 kunye nama-3 ehlanganisiweyo. Igqabi lesibini lihlala likhupha ngokungapheliyo kwaye livalwe kakhulu. Amagqabi amancinci aphezulu, ovaliweyo, okanye i-oval. Umgca, malunga ne-2 cm ubude, nge-blunt okanye i-bitp apex kunye nemiphetho ecocekileyo. I-inflorescence yayo ibulwe ngumdyarho, kunye namagqabi e-terminal okanye amagqabi; Iibhuloti zenziwe ngokubanzi i-lancealate; Iintyatyambo zibomvu-ezimfusa kwaye zikhule ngokuthe tyaba kwi-pericings ezinxibisayo, ezimalunga ne-6 mm ubude; I-calyx iwela kwangoko; I-petals i-4 kwaye i-whorls yangaphandle i-2 amacandelo amakhulu kancinane, ngemiphetho epinki kunye neziko le-bluish-flople. Kukho icandelo elinye elingaphezulu, kwaye umsila wawudlulisela kwi-spur ende. Ubude be-spur malunga nesiqingatha sobude bebonke. I-Oppents ezi-2 zangaphakathi zincinci kunezinyuko ezi-2 zangaphandle. Isiphelo esingaphezulu sisifuba esimfusa kwaye siphilisiwe, kwaye iqhekeza elisezantsi lipinki; Izitokhwe ziyi-6, kwaye iifiliment zixhunyiwe kwiibhulethi ezimbini, nganye inee-3 i-i-i-i-i-i-i-i-i-i-i-i-i-i-i-i-i-hies; I-ovary iflethi-chestrical, isitayile simfutshane kwaye sithambile, kwaye ihlazo liyi-2, njengebhabhathane elincinci. Iziqhamo zayo yicaphule. I-Corydalis iveliswa ikakhulu ezintabeni okanye zengca. Iindawo eziphambili zokuvelisa zibandakanya iZhejiang, Hebei, Shandong, Jiangsu, nakwezinye iindawo.
| Uhlalutyo | Ukucaciswa |
| I-assay | I-Tetrarahydropatine ≥98% |
| Imbonakalo | I-polle ye-tyheli emfutshane yomgubo omhlophe |
| I-ash | ≤0.5% |
| Ukufuma | ≤5.0% |
| Izibulala-zinambuzane | Engalunganga |
| Izinyithi ezinzima | ≤10ppm |
| Pb | ≤2.0ppm |
| As | ≤2.0ppm |
| Ivumba | Phawula |
| Ubungakanani bentsundu | I-100% nge-80 mesh |
| Microbiological : | |
| Iyonke yeBacteria | ≤1000cfu / g |
| Fungu | ≤100cfu / g |
| Salmgosse | Engalunganga |
| Coli | Engalunganga |
Nazi amashishini emveliso yemveliso yeTetrarahdroPatine (i-STP):
1. Amayeza:I-Thp isetyenziswa kumzi-mveliso wamachiza okuphuhlisa amayeza olawulo lweentlungu kunye neziyobisi ze-neuroprouctive.
2. I-Nutraceuticals:I-TIP isetyenziswa kumzi-mveliso wesondlo wokuqulunqa incedisi ekujoliswe kuyo isiqabu sentlungu kunye nenkxaso yempilo ka-Gastric.
3. I-Biotechnology:I-STP ifumana izicelo kwi-biotechnology yophando kwi-antiplaigles parapies kunye ne-addring yonyango olunokubakho.
4. Uqwalaselo lwezeMpilo:I-TIP ifakiwe kwiimveliso zempilo zokulawulwa kwekhoboka kunye neempawu zokurhoxa ezinxulumene ne-opioid kunye ne-opimoid.
5. Iicosmeuticals:I-Thp iphononongwa kwi-cosproceuticals yempilo yolusu olunokubakho kunye nokulwa i-anti-insulimatory.
Lo mveliso ubonakalisa usetyenziso oluvinyeneyo lweTetrahydroPatine (i-STP) kuPhuhliso lweMveliso kunye noPhando.
Iimveliso zethu zenziwa zisebenzisa amanyathelo aphantsi olawulo lomgangatho kwaye zilandele imigangatho ephezulu yeenkqubo zemveliso. Sibeka phambili ukhuseleko kunye nomgangatho wemveliso yethu, ukuqinisekisa ukuba ifezekisa iimfuno zomthetho kunye nezatifikethi zeshishini. Oku kuzinikela kwimigangatho esemgangathweni yokuseka ukuthembana kunye nokuzithemba ekuthembekeni kwemveliso yethu. Inkqubo yemveliso ngokubanzi yile ilandelayo:
Ukugcinwa:Gcina kwindawo epholileyo, eyomileyo necocekileyo, husela ekumakeni kunye nokukhanya ngokuthe ngqo.
Iphakheji ye-Bulk:20~25kg / idrum.
Ixesha lokukhokhela:Iintsuku ezisi-7 emva kolungelelwano lwakho.
Beka ubomi kwishelufa:iminyaka eyi-2.
I-tesk:Inkcazo ngokwezifiso inokufezekiswa.
Chaza
Ngaphantsi kwe-100kg, i-3-5 yantwana
Umnyango kwinkonzo yendlu kulula ukuthabatha iimpahla
Ngolwandle
Ngaphezulu kwe-300kg, malunga neentsuku ezingama-30
I-Port ukuya kwi-Port Point Conseker Bricker efunekayo
Ngomoya
I-100kg-1000kg, 5-7 days
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