I. Intshayelelo
I. Intshayelelo
Indima yesondlo ekugcineni impilo entle ayinakujongwa. Enye into enamandla eye yatsala ingqalelo ngenxa yeenzuzo zayo zentliziyo yilei-allicinKule nqaku, sijonga iipropati kunye neenzuzo ze-allicin kwimpilo yentliziyo. I-Allicin yikhompawundi esebenzayo efumaneka kwigalikhi, eyaziwa ngevumba layo elikhethekileyo kunye nencasa. Yenziwa xa igalikhi ityunyuziwe okanye inqunyulwe, ikhupha ikhompawundi yesalfure ebizwa ngokuba yi-alliinase ekhuthaza ukuguqulwa kwe-alliin ibe yi-allicin. Impilo yentliziyo ibalulekile kwimpilo-ntle iyonke, njengoko intliziyo iphambili ekupompeni igazi kunye nezondlo emzimbeni wonke. Ukugcina intliziyo esempilweni kunokunciphisa umngcipheko wezifo zentliziyo ezifana nokuhlaselwa yintliziyo kunye nokubetha, okwenza kube yimfuneko ukuphonononga amayeza endalo anokubakho njenge-allicin.
II. Yintoni iAllicin?
Inkcazo kunye neMithombo
I-Allicin yikhompawundi equlathe i-sulfur ebonisa iipropati ezinamandla zokulwa ne-antimicrobial kunye ne-antioxidant. Ngaphandle kwegalikhi, i-allicin inokufumaneka nakwamanye amalungu osapho lwe-Allium, kuquka u-anyanisi, iileeks kunye nee-shallots.
Iingenelo zeMpilo ze-Allicin
Iingenelo zempilo ze-allicin zidlulela ngaphaya kweempawu zayo zokulwa ne-antimicrobial ezibhalwe kakuhle. Le khompawundi imangalisayo ibingumxholo wophando olunzulu, ityhila iingenelo ezininzi zomzimba ezinokuphucula kakhulu impilo iyonke. Enye yezona mpawu zibalulekileyo ze-allicin kukwazi kwayo ukulwa ne-antioxidant. Ii-antioxidants zibalulekile ekuthomalaliseni ii-free radicals—ii-molecule ezingazinzanga ezinokubangela uxinzelelo lwe-oxidative, ezikhokelela ekonakaleni kweseli kwaye zinegalelo ekuphuhlisweni kwezifo ezingapheliyo. Ngokususa ezi zinto zinobungozi, i-allicin inceda ukukhusela umzimba ekonakaleni kwe-oxidative, ngaloo ndlela ikhuthaza ukuthembeka kweseli kunye nobomi obude.
Ukongeza kwi-antioxidant yayo enamandla, i-allicin ineziphumo eziphawulekayo zokulwa nokuvuvukala. Ukudumba okungapheliyo kuqatshelwa ngakumbi njengesandulela seengxaki ezahlukeneyo zempilo, kubandakanya isifo sentliziyo, isifo seswekile, kunye nomhlaza othile. Ukukwazi kwe-Allicin ukuguqula iindlela zokudumba kunokunceda ukunciphisa lo mngcipheko. Ngokuthintela ukuveliswa kwee-cytokines kunye nee-enzymes ezibangela ukuvuvukala, i-allicin inokunciphisa ukudumba emzimbeni wonke, ikhuthaze imeko-bume yangaphakathi esempilweni.
Ngaphezu koko, i-allicin ibonakalisiwe ineempawu zokunciphisa amafutha emzimbeni, eziluncedo kakhulu kwimpilo yentliziyo. Amanqanaba aphezulu e-low-density lipoprotein (LDL) cholesterol kunye ne-triglycerides zizinto ezibalulekileyo ezibangela isifo sentliziyo. Uphando lubonisa ukuba i-allicin inokunceda ukunciphisa amanqanaba e-cholesterol iyonke kwaye iphucule umlinganiselo we-HDL (high-density lipoprotein) kwi-LDL cholesterol. Esi siphumo sokuguqula amafutha emzimbeni sibalulekile ekugcineni inkqubo yentliziyo esempilweni kunye nokunciphisa umngcipheko we-atherosclerosis, imeko ebonakaliswa kukuqokelelana kwamafutha kwimithambo yegazi.
Uhlobo lwe-Allicin olunemiba emininzi lukwafikelela nakwindima yayo enokubakho ekulawuleni uxinzelelo lwegazi. Uxinzelelo lwegazi oluphezulu, okanye uxinzelelo lwegazi oluphezulu, luyinto ephambili ebangela isifo sentliziyo kunye nesifo sohlangothi. Izifundo zibonise ukuba i-allicin inokubangela i-vasodilation, inkqubo apho imithambo yegazi iphumla kwaye ikhula khona, ngaloo ndlela iphucula ukuhamba kwegazi kwaye inciphise uxinzelelo lwegazi. Esi siphumo siluncedo kakhulu kubantu abanexinzelelo lwegazi oluphezulu, njengoko sinokukhokelela ekuphuculeni okukhulu kwimpilo yentliziyo.
Ngaphezu koko, i-allicin inokudlala indima kwi-metabolism yeswekile, nto leyo eyenza ukuba ibe ngumhlobo obalulekileyo kubantu abanesifo seswekile okanye abo basengozini yokuhlaselwa sesi sifo. Uphando lubonisa ukuba i-allicin inokuphucula uvakalelo lwe-insulin kwaye iphucule ulawulo lwe-glycemic, ngaloo ndlela incede ekulawuleni amanqanaba eswekile egazini. Oku kubaluleke kakhulu, njengoko iswekile yegazi engalawulwayo inokukhokelela kwiingxaki ezininzi, kubandakanya imiba yentliziyo.
Iziphumo eziqokelelweyo ze-allicin kuxinzelelo lwe-oxidative, ukudumba, iiprofayili zamafutha, uxinzelelo lwegazi, kunye ne-glucose metabolism zigxininisa amandla ayo njengendlela epheleleyo yempilo. Njengekhompawundi yendalo enembali etyebileyo yokusetyenziswa kumayeza endabuko, i-allicin inika ukhetho olunomtsalane kwabo bafuna ukuphucula impilo yentliziyo yabo kunye nokuphila kakuhle iyonke. Ukufakwa kwayo kukutya okunesondlo, kunye nezinye iindlela zokuphila ezisempilweni, kunokubonelela ngesiphumo sokusebenzisana esikhuthaza ubomi obude kunye namandla.
III. I-Allicin kunye neMpilo yeNtliziyo
Indlela Yokusebenza
Iindlela ezichaphazela ngayo impilo yentliziyo i-allicin zintsonkothile kwaye zahlukahlukene. I-Allicin ikhuthaza ukujikeleza kwegazi, yandisa imithambo yegazi ukuphucula ukuhamba kwegazi kunye nokunciphisa uxinzelelo lwegazi. Esi siphumo sibangelwa ikakhulu kukukhululwa kwe-nitric oxide, ekhulula iiseli zemisipha ezithambileyo kwiindonga zemithambo yegazi. Ngokuphucula ukuhamba kwegazi, i-allicin ayithobeli nje uxinzelelo lwegazi kodwa ikwaqinisekisa ukuba amalungu abalulekileyo afumana ioksijini kunye nezondlo ezaneleyo.
Ukongeza, i-allicin inokuthintela ukuhlangana kweeplatelet, nto leyo ebaluleke kakhulu ekuthinteleni i-thrombosis—into ebalulekileyo ebangela ukuhlaselwa yintliziyo kunye nokubetha kwentliziyo. Ngokuphazamisa ukusebenza kweeplatelet, i-allicin inceda ukugcina ukuhamba kwegazi kuhamba kakuhle, inciphisa umngcipheko wokwakheka kwamahlwili. Ipropati yayo yokulwa nokuvaleka kwemithambo yegazi iluncedo ngakumbi kwabo basengozini yeziganeko zentliziyo.
Ngaphezu koko, iipropati ze-allicin ze-antioxidant zidlala indima ebalulekileyo ekulweni noxinzelelo lwe-oxidative, olunegalelo kwizifo zentliziyo. I-Allicin isusa ii-free radicals, ikhusela iiseli ze-endothelial—iiseli ezigqume imithambo yegazi—ekonakaleni kwe-oxidative. Esi siphumo sokukhusela sibalulekile ekugcineni umsebenzi we-endothelial, obaluleke kakhulu kwimpilo yentliziyo.
Iziphumo zoPhando kunye noPhando
Izifundo ezininzi zibonise iingenelo ze-allicin kwintliziyo, zixhasa ukubandakanywa kwayo kwizicwangciso zempilo yentliziyo. Umzekelo, uhlalutyo lwe-meta lubonise ukuba ukongezwa kwegalikhi, okutyebileyo kwi-allicin, kunciphisa kakhulu uxinzelelo lwegazi kwizigulana ezine-hypertension. Ukulawula uxinzelelo lwegazi kubalulekile ekuthinteleni izifo zentliziyo.
Olunye uphando lubonise amandla e-allicin okunciphisa amanqanaba e-cholesterol kunye ne-triglyceride, okunciphisa umngcipheko we-atherosclerosis. I-cholesterol ephezulu yinto eyaziwayo ebangela ukwakheka kwe-plaque kwimithambo yegazi, nto leyo ekhokelela kwimiba yentliziyo. Ngokuphucula iiprofayili zamafutha, i-allicin inegalelo kwinkqubo yentliziyo enempilo.
Ngaphezu koko, uphando lubonisa ukuba i-allicin inokuphucula ukusebenza kwe-endothelial. I-garlic extract ifunyenwe iphucula ukujikeleza kwegazi okuxhomekeke kwi-endothelial, nto leyo ebonisa ukuba i-allicin inokubuyisela ukusebenza okuqhelekileyo kwemithambo yegazi kwabo banempilo yentliziyo ebuthathaka. Ezi ziphumo zigxininisa indima ethembisayo ye-allicin kwimpilo yentliziyo.
Iingenelo ezinokubakho kwiMpilo yeNtliziyo
I-Allicin ineengenelo ezininzi kwimpilo yentliziyo, kubandakanya ukuphucula iiprofayili zamafutha, ukwehla koxinzelelo lwegazi, kunye nokusebenza kakuhle kwe-endothelial. Amandla ayo okunciphisa i-cholesterol ye-LDL kunye ne-triglycerides ngelixa inyusa i-cholesterol ye-HDL inciphisa umngcipheko we-atherosclerosis kunye neziganeko zentliziyo.
Iimpawu ze-Allicin zokulwa nokuvuvukala zinokunceda ekunciphiseni ukudumba okungapheliyo, okwaziwayo ukuba negalelo kwizifo zentliziyo. Ngokunciphisa iimpawu zokudumba emzimbeni, i-allicin inokunciphisa umngcipheko weemeko ezifana nesifo semithambo yegazi kunye nokusilela kwentliziyo.
Ukuqukumbela, iziphumo ezininzi ze-allicin kuxinzelelo lwegazi, iiprofayili zamafutha, umsebenzi we-endothelial, kunye nokudumba kwenza ukuba ibe lukhetho olunomtsalane lokuphucula impilo-ntle yentliziyo. Njengoko uphando luqhubeka, i-allicin inokuba yintsika kwizicwangciso zokutya ezijolise ekukhuthazeni impilo yentliziyo.
IV. Iingozi kunye neziphumo ebezingalindelekanga ze-Allicin
Unxibelelwano olunokwenzeka kunye namayeza
Nangona i-allicin ithathwa njengekhuselekileyo xa ityiwa ekutyeni, kufuneka uqaphele xa kufikwa kwizongezo okanye kwiintlobo ze-allicin ezixineneyo. La mayeza axineneyo anokusebenzisana namayeza ahlukeneyo, ngakumbi amayeza okuthintela ukugabha kwegazi okanye amayeza okunciphisa igazi afana ne-warfarin kunye ne-aspirin. I-Allicin inamandla okuphucula imiphumo yala mayeza, okwandisa umngcipheko wokopha. Olu nxibelelwano luxhalabisa ngakumbi abantu abenza utyando okanye abo baneengxaki zokopha.
Ukongeza, i-allicin inokuchaphazela imetabolism yamayeza athile acutshungulwa sisibindi. Ingachaphazela umsebenzi wee-enzymes ze-cytochrome P450, ezidlala indima ebalulekileyo kwimetabolism yamayeza. Olu tshintsho lunokukhokelela ekwandeni kwetyhefu okanye ekunciphiseni ukusebenza kakuhle kwamayeza, kuxhomekeke kwiyeza elithile elibandakanyekayo. Ke ngoko, kuyacetyiswa ukuba udibane nomboneleli wezempilo ngaphambi kokuba ufake izongezo ze-allicin kwirejimeni yakho, ingakumbi ukuba uthatha amayeza kagqirha okanye uneengxaki zempilo ezingabonakaliyo.
Iziphumo ebezingalindelekanga zokusetyenziswa kwe-Allicin
Kwabanye abantu, iidosi eziphezulu ze-allicin zinokubangela iingxaki zesisu, kubandakanya isitshiso sentliziyo, ukudumba, okanye ukungagayi kakuhle kokutya. Ezi ziphumo zingabonakala ngakumbi kwabo banomdla kwiikhompawundi zegalikhi okanye zesulfure. Nangona ukutya ukutya okune-allicin eninzi kudla ngokunyanyezelwa kakuhle, ukutya kakhulu—ingakumbi xa kusenziwa ngesondlo—kunokwenza ezi mpawu zibe mandundu.
Ngaphezu koko, ivumba elinamandla elinxulunyaniswa ne-allicin linokuba yinto engathandekiyo kwabanye, nto leyo ekhokelela ekungonwabini okanye ekubeni neentloni. Eli vumba livela kwi-allicin kwaye linokuhlala lisempumlweni naselusu, nto leyo enokuthintela abantu ekutyeni rhoqo igalikhi okanye ukutya okutyebileyo kwi-allicin.
Kubalulekile ukujongana nokusetyenziswa kwe-allicin ngokulinganisela kunye nokuqonda amanqanaba okunyamezelana komntu ngamnye. Ukuqala ngezixa ezincinci kunye nokunyusa kancinci kancinci ukutya kunokunceda ukunciphisa iziphumo ebezingalindelekanga. Kwabo bafumana iziphumo ezibi, kunokuba luncedo ukubonisana neengcali zezempilo ukuze kuxoxwe ngezinye iindlela ze-allicin okanye ezinye iindlela zokutya.
Ngamafutshane, nangona i-allicin ineenzuzo ezininzi zempilo, kubalulekile ukuqaphela ukunxibelelana kwayo namayeza kunye nokuba nemiphumo emibi inokubakho. Ngokusebenzisa unonophelo kunye nokufuna ulwalathiso lobuchwephesha, abantu banokuyifaka ngokukhuselekileyo i-allicin kwizidlo zabo kwaye bayonwabele iingenelo zayo zentliziyo ngaphandle komngcipheko ongafanelekanga.
V. Indlela yokufaka i-Allicin kwiDiet
Ukutya Okuphezulu kwiAllicin
Ukuze ufumane iingenelo ze-allicin, faka igalikhi, u-anyanisi, iilikhi, kunye neeshallots ekutyeni kwakho kwemihla ngemihla. Oku kutya akupheleli nje ekunikeni i-allicin kodwa kukwakho nezinye izinto eziluncedo ezixhasa impilo yentliziyo kunye nempilo-ntle iyonke.
Iingcebiso Zokupheka Nokulungiselela
Ukuze ufumane i-allicin eninzi kwigalikhi, yityumze okanye uyinqumle uze uyivumele ihlale imizuzu embalwa ngaphambi kokuba uyipheke. Ukupheka igalikhi kumaqondo obushushu aphantsi ixesha elifutshane kunokunceda ukugcina i-allicin engakumbi, ukuqinisekisa ukuba ufumana okuninzi kule nxalenye iluncedo.
Isiphelo
Ukuqukumbela, i-allicin ibonisa ithemba njengesithako sendalo esineengenelo ezinokubakho kwimpilo yentliziyo. Ngokufaka ukutya okutyebileyo kwi-allicin ekutyeni kwakho kunye nokulandela iingcebiso ezisekelwe kubungqina, unokukwazi ukuxhasa impilo-ntle yakho yentliziyo kunye nokunciphisa umngcipheko weengxaki ezinxulumene nentliziyo.
Uphando olongezelelekileyo malunga neendlela ezithile ze-allicin kwimpilo yentliziyo, iidosi ezifanelekileyo, kunye nemiphumo yexesha elide lufanelekile ukuze siqonde ngakumbi le nto inomdla. Uphando oluqhubekayo ngendima ye-allicin ekugcineni impilo yentliziyo lunokukhokelela kwizicwangciso ezintsha zokuthintela nezonyango kwizifo zentliziyo.
Qhagamshelana nathi
UGrace Hu (uMphathi weNtengiso)grace@biowaycn.com
UCarl Cheng (i-CEO/uMphathi)ceo@biowaycn.com
Iwebhusayithi:www.biowaynutrition.com
Ixesha leposi: Oktobha-30-2024
