Iindaba-Ngaba iAllicin iluncedo kwiMpilo yeNtliziyo?

I. Intshayelelo

Indima yesondlo ekugcineni impilo iphezulu ayinakujongelwa phantsi. Enye ikhompawundi enamandla eye yafumana ingqwalasela kwiinzuzo zayo ezinokubakho kwintliziyoiallicin. Kweli nqaku, sijonga kwiipropati kunye neenzuzo ze-allicin kwimpilo yentliziyo. I-Allicin yi-bioactive compound efumaneka kwigalikhi, eyaziwa ngokuba yivumba layo elahlukileyo kunye nencasa. Yenziwa xa igalikhi ityunyuziwe okanye inqunyulwe, ikhupha i-sulfur compound ebizwa ngokuba yi-alliinase eyenza ukuguqulwa kwe-alliin kwi-allicin. Impilo yentliziyo ibalulekile kwimpilontle ngokubanzi, njengoko intliziyo ingundoqo ekumpompeni igazi kunye nezondlo emzimbeni wonke. Ukugcina intliziyo esempilweni kunokunciphisa umngcipheko wezifo zentliziyo ezifana nokuhlaselwa sisifo sentliziyo kunye nokubetha, nto leyo eyenza kube yimfuneko ukuphonononga amayeza endalo anokubakho njenge-allicin.

II. Yintoni iAllicin?

Ingcaciso kunye neMithombo

I-Allicin yi-compound enesulfure ebonisa iimpawu ezinamandla ze-antimicrobial kunye ne-antioxidant. Ngaphandle kwegalikhi, i-allicin inokufumaneka kwamanye amalungu osapho lwe-Allium, kuquka itswele, iiliki, kunye neshallots.

IiNzuzo zeMpilo ze-Allicin

Iinzuzo zezempilo ze-allicin zidlulela ngaphaya kweepropathi zayo zokulwa neentsholongwane ezibhalwe kakuhle. Le khompawundi imangalisayo ibe ngumxholo wophando olubanzi, eveza i-plethora yeenzuzo zomzimba ezinokuphucula kakhulu impilo yonke. Enye yezona mpawu zinyanzelisayo ze-allicin ngamandla ayo e-antioxidant. I-Antioxidants ibalulekile ekunciphiseni i-radicals yamahhala-i-molecule ezingazinzanga ezinokubangela uxinzelelo lwe-oxidative, olukhokelela kumonakalo weselula kunye negalelo ekuphuhliseni izifo ezingapheliyo. Ngokukhupha ezi zinto ziyingozi, i-allicin inceda ukukhusela umzimba kumonakalo we-oxidative, ngaloo ndlela ikhuthaza ingqibelelo yeselula kunye nokuphila ixesha elide.

Ukongeza kubuchule bayo be-antioxidant, i-allicin ibonisa imiphumo ephawulekayo yokuchasana nokudumba. Ukudumba okungapheliyo kuya kubonwa njengesandulela kwimiba eyahlukeneyo yezempilo, kubandakanya nesifo sentliziyo, isifo seswekile, kunye nomhlaza othile. Ukukwazi kuka-Allicin ukulungelelanisa iindlela zokuvuvukala kunokuncedisa ukunciphisa lo mngcipheko. Ngokuthintela ukuveliswa kwe-cytokines e-pro-inflammatory kunye ne-enzymes, i-allicin inokunciphisa ukuvuvukala kuwo wonke umzimba, ikhuthaze indawo ephilileyo yangaphakathi.

Ngaphezu koko, i-allicin ibonakaliswe ukuba ineempawu zokunciphisa i-lipid, eziluncedo kakhulu kwimpilo yentliziyo. Amanqanaba aphezulu e-low-density lipoprotein (LDL) ye-cholesterol kunye ne-triglycerides yimiba ebalulekileyo yengozi yesifo senhliziyo. Uphando lubonisa ukuba i-allicin inokunceda ukunciphisa amanqanaba e-cholesterol epheleleyo kunye nokuphucula umlinganiselo we-HDL (high-density lipoprotein) ukuya kwi-LDL cholesterol. Esi siphumo se-lipid-modulating sibalulekile ekugcineni inkqubo ye-cardiovascular system enempilo kunye nokunciphisa umngcipheko we-atherosclerosis, imeko ebonakala ngokunyuka kwamafutha kwi-artery.

Indalo eneenkalo ezininzi ka-Allicin ikwanwenwela kwindima yayo enokubakho ekulawuleni uxinzelelo lwegazi. Uxinzelelo lwegazi, okanye uxinzelelo lwegazi oluphezulu, ngumngcipheko omkhulu wesifo senhliziyo kunye nesifo. Uphononongo lubonise ukuba i-allicin inokubangela i-vasodilation, inkqubo apho imithambo yegazi iphumla kwaye yande, ngaloo ndlela iphucula ukuhamba kwegazi kunye nokunciphisa uxinzelelo lwegazi. Esi siphumo siluncedo kakhulu kubantu abane-hypertension, njengoko kunokukhokelela ekuphuculeni okubalulekileyo kwimpilo yentliziyo.

Ngapha koko, i-allicin inokudlala indima kwi-glucose metabolism, iyenze ibe liqabane elixabisekileyo kubantu abanesifo seswekile okanye abo basengozini yokuphuhlisa imeko. Uphando lubonisa ukuba i-allicin inokuphucula ukuvakalelwa kwe-insulin kunye nokuphucula ulawulo lwe-glycemic, ngaloo ndlela inceda ekulawuleni amanqanaba eswekile yegazi. Oku kubaluleke ngakumbi, njengoko iswekile yegazi engalawulekiyo inokukhokelela kwinkitha yeengxaki, kubandakanywa nemiba ye-cardiovascular.

Iziphumo eziqokelelweyo ze-allicin kuxinzelelo lwe-oxidative, ukuvuvukala, iiprofayili zelipid, uxinzelelo lwegazi, kunye ne-glucose metabolism igxininisa amandla ayo njengendlela epheleleyo yempilo. Njengekhompawundi yendalo enembali etyebileyo yokusetyenziswa kumayeza esintu, i-allicin inika inketho enyanzelekileyo kwabo bafuna ukukhulisa impilo yentliziyo kunye nempilo yonke. Ukufakwa kwayo kwisidlo esinokulinganisela, kunye nezinye iindlela zokuphila ezinempilo, kunokubonelela ngempembelelo ye-synergistic ekhuthaza ubomi obude kunye namandla.

III. I-Allicin kunye neMpilo yeNtliziyo

Indlela yokwenza

Iindlela apho i-allicin ichaphazela impilo yentliziyo intsonkothile kwaye yahlukile. I-Allicin ikhuthaza i-vasodilation, yandisa imithambo yegazi ukuphucula ukuhamba kwegazi kunye nokunciphisa uxinzelelo lwegazi. Esi siphumo senziwa ngokuyintloko ngokukhululwa kwe-nitric oxide, ekhulula iiseli ze-muscle ezigudileyo kwiindonga zemithambo yegazi. Ngokwandisa ukuhamba kwegazi, i-allicin ayigcini nje ukuthoba uxinzelelo lwegazi kodwa iqinisekisa ukuba amalungu abalulekileyo afumana ioksijini eyaneleyo kunye nezondlo.
Ukongezelela, i-allicin inokuthintela ukuhlanganiswa kweeplatelet, okubalulekileyo ekuthinteleni i-thrombosis-into ebalulekileyo yomngcipheko wokuhlaselwa yintliziyo kunye nokubetha. Ngokuphazamisa ukusebenza kweplatelet, i-allicin inceda ukugcina ukuhamba kakuhle kwegazi, ukunciphisa umngcipheko wokwakhiwa kwe-clot. Ipropathi yayo ye-antithrombotic inenzuzo ngokukodwa kwabo basengozini yeziganeko ze-cardiovascular.
Ngapha koko, iipropathi ze-allicin ze-antioxidant zidlala indima ebalulekileyo ekulweni uxinzelelo lwe-oxidative, igalelo kwizifo zentliziyo. I-Allicin ikhupha i-radicals yamahhala, ikhusela iiseli ze-endothelial-iiseli ezidibanisa imithwalo yegazi-kumonakalo we-oxidative. Esi siphumo sokukhusela sibalulekile ekugcineni umsebenzi we-endothelial, obalulekileyo kwimpilo ye-cardiovascular.

Izifundo kunye neziphumo zoPhando

Izifundo ezininzi ziye zagxininisa iinzuzo ze-cardiovascular of allicin, ezixhasa ukubandakanywa kwayo kwizicwangciso zempilo yentliziyo. Ngokomzekelo, i-meta-analysis ibonise ukuba i-garlic supplementation, ecebileyo kwi-allicin, yanciphisa kakhulu uxinzelelo lwegazi kwizigulane eziphezulu. Ukulawula uxinzelelo lwegazi ngundoqo ekuthinteleni isifo senhliziyo.
Olunye uphando lubonise amandla e-allicin ekunciphiseni i-cholesterol kunye namanqanaba e-triglyceride, ukunciphisa umngcipheko we-atherosclerosis. I-cholesterol ephezulu yinto eyaziwayo yomngcipheko wokwakhiwa kwe-plaque kwimithambo yegazi, ekhokelela kwimicimbi yentliziyo. Ngokuphucula iiprofayili ze-lipid, i-allicin igalelo kwinkqubo ye-cardiovascular system.
Ngaphezu koko, uphando lubonisa ukuba i-allicin inokuphucula umsebenzi we-endothelial. I-Garlic extract yafunyanwa ukuphucula i-vasodilation exhomekeke kwi-endothelial, iphakamisa ukuba i-allicin inokubuyisela umsebenzi oqhelekileyo we-vascular kulabo abanempilo yentliziyo esengozini. Ezi ziphumo zigxininisa indima ethembisayo ye-allicin kwimpilo yentliziyo.

IiNzuzo ezinokubakho kwiMpilo yeNtliziyo

I-Allicin ibonelela ngeenzuzo ezininzi kwimpilo yentliziyo, kubandakanya ukuphuculwa kweeprofayili zelipid, ukunciphisa uxinzelelo lwegazi, kunye nomsebenzi ophuculweyo we-endothelial. Ikhono layo lokunciphisa i-cholesterol ye-LDL kunye ne-triglycerides ngelixa ukwandisa i-cholesterol ye-HDL kunciphisa umngcipheko we-atherosclerosis kunye neziganeko ze-cardiovascular.
Iipropathi ze-Allicin zokuchasa ukudumba zisenokunceda ekunciphiseni ukudumba okungapheliyo, into eyaziwa ngokuba negalelo kwizifo zentliziyo. Ngokunciphisa iimpawu zokukrala emzimbeni, i-allicin inokunciphisa umngcipheko weemeko ezifana nesifo se-coronary artery kunye nokusilela kwentliziyo.
Ukuqukumbela, iziphumo ezininzi ze-allicin kuxinzelelo lwegazi, iiprofayili ze-lipid, umsebenzi we-endothelial, kunye nokuvuvukala kwenza kube yinto enyanzelekileyo yokuphucula impilo ye-cardiovascular. Njengoko uphando luqhubela phambili, i-allicin ingaba sisiseko kwizicwangciso zokutya ezijoliswe ekukhuthazeni impilo yentliziyo.

IV. Imingcipheko kunye neziphumo ebezingalindelekanga ze-Allicin

Ukusebenzisana okunokwenzeka kunye naMayeza

Ngelixa i-allicin ngokuqhelekileyo ithathwa njengekhuselekile xa isetyenziswe kwifom yokutya, isilumkiso sifanelekile xa kuziwa kwizongezelelo okanye iindlela ezigxininisiweyo ze-allicin. La malungiselelo agxininisiweyo anokunxibelelana namayeza ahlukeneyo, ngakumbi i-anticoagulants okanye i-blood thinners efana ne-warfarin kunye ne-aspirin. I-Allicin inamandla okuphucula iziphumo zala mayeza, ukwandisa umngcipheko wokuphuma kwegazi. Olu nxibelelwano lubhekiselele ngakumbi kubantu abenza utyando okanye abo banengxaki yokopha.
Ukongezelela, i-allicin inokuchaphazela i-metabolism yamachiza athile acutshungulwa sisibindi. Inokuphembelela umsebenzi we-cytochrome P450 enzymes, edlala indima ebalulekileyo kwimetabolism yeziyobisi. Olu tshintsho lunokukhokelela ekunyukeni kwetyhefu okanye ukuncipha kokusebenza kwamayeza, ngokuxhomekeke kwiyeza elithile elibandakanyekayo. Ngoko ke, kuyacetyiswa ukuba udibane nomboneleli wezempilo ngaphambi kokuba udibanise izongezo ze-allicin kwirejimeni yakho, ngakumbi ukuba uthatha amayeza kagqirha okanye uneemeko zempilo eziphantsi.

Iziphumo eziPhakamileyo zokusetyenziswa kwe-Allicin

Kwabanye abantu, iidosi eziphezulu ze-allicin zinokukhokelela kwimiba yesisu, kubandakanya isitshisa, ukuqunjelwa, okanye ukugabha. Ezi ziphumo zecala zinokuvakaliswa ngokukodwa kwabo banomdla kwigalikhi okanye iikhompawundi ezinesulfure. Nangona ukusetyenziswa ngokulinganayo kokutya okutyebileyo kwe-allicin ngokuqhelekileyo kunyamezelwa kakuhle, ukutya okugqithisileyo-ingakumbi kwifomu yokuncedisa-kunokunyusa ezi zimpawu.
Ngaphezu koko, iphunga elimnandi elinxulumene ne-allicin linokuthi likhuphe abanye, libangele ukungahambi kakuhle kwentlalo okanye ukuhlazeka. Eli vumba liyimveliso yendalo ye-allicin kwaye linokuhlala phezu komphefumlo kunye nolusu, olunokuthi luthintele abantu ukuba batye ikonofile okanye ukutya okutyebileyo kwe-allicin rhoqo.
Kubalulekile ukujongana nosetyenziso lwe-allicin ngokumodareyitha kunye nokwazisa amanqanaba okunyamezela komntu ngamnye. Ukuqala ngeemali ezincinci kunye nokonyusa kancinci kancinci kunokunceda ukunciphisa iziphumo ebezingalindelekanga. Kwabo bafumana iziphumo ezingathandekiyo, kunokuba luncedo ukudibana nengcali yezempilo ukuxoxa ngeminye imithombo ye-allicin okanye ezinye izilungiso zokutya.
Isishwankathelo, ngelixa i-allicin ibonelela ngeenzuzo ezininzi zempilo, kubalulekile ukuba uqaphele ukusebenzisana kwayo okunokubakho kunye namayeza kunye nokubakho kweziphumo ebezingalindelekanga. Ngokulumka kunye nokufuna isikhokelo sobuchwephesha, abantu banokufaka ngokukhuselekileyo i-allicin kukutya kwabo kwaye bayonwabele izibonelelo zayo zentliziyo ngaphandle komngcipheko ongafanelekanga.

V. Indlela yokudibanisa i-Allicin kwiDiet

Ukutya okuphezulu kwi-Allicin

Ukusebenzisa izibonelelo ze-allicin, faka igalikhi, itswele, iiliki, kunye neshaloti kwisidlo sakho semihla ngemihla. Oku kutya akuboneleli kuphela nge-allicin kodwa kunye noluhlu lwezinye iikhompawundi ezinenzuzo ezixhasa impilo yentliziyo kunye nempilo yonke.

Iingcebiso zokupheka kunye nokulungiselela

Ukwandisa umxholo we-allicin kwigalikhi, yiqhekeze okanye uyinqumle kwaye uyivumele ukuba ihlale imizuzu embalwa ngaphambi kokupheka. Ukupheka igalikhi kumaqondo obushushu aphantsi ixesha elifutshane kunokunceda ukugcina i-allicin eninzi, ukuqinisekisa ukuba ufumana okuninzi kule khompawundi enenzuzo.

Ukuqukumbela

Ukuqukumbela, i-allicin ibonisa isithembiso njengesithako sendalo esineenzuzo ezinokubakho kwimpilo yentliziyo. Ngokubandakanya ukutya okutyebileyo kwe-allicin ekudleni kwakho kunye nokulandela iingcebiso ezisekelwe kubungqina, unokukwazi ukuxhasa impilo yakho ye-cardiovascular and ukunciphisa umngcipheko weengxaki ezinxulumene nentliziyo.
Uphando olongezelelweyo kwiindlela ezithile ze-allicin kwimpilo yentliziyo, iidosi ezifanelekileyo, kunye neziphumo zexesha elide zifanelekile ukuqinisa ukuqonda kwethu le khompawundi enomdla. Uphando oluqhubekayo malunga nendima ye-allicin ekugcineni impilo yentliziyo inokukhokelela kwizicwangciso ezintsha zokukhusela kunye nezonyango kwizifo zentliziyo.