Umzi-mveliso unyulu ococekileyo β-nicotinamide adenine dieucceotide (nead)
β-nicotinamide adenine dinucleotide (i-nad) yi-coenanme efumaneka kuzo zonke iiseli eziphilayo, edlala indima ebalulekileyo kwiinkqubo ezahlukeneyo zemetabolic. Kuyimfuneko ukuba imveliso yamandla, ukulungiswa kwe-DNA, kunye neseli. I-Nad ikhona kwiifom ezimbini: I-NAD + kunye ne-nadh, ebandakanyekayo kwi-Renox Reaction, ukudlulisela ii-elektroniki ngexesha lokuhamba kweMetabol. I-Nad ibalulekile ekugcineni umsebenzi weselula kunye nempilo iyonke, kwaye amanqanaba ayo anokuba nefuthe kwiinkqubo ezahlukeneyo zomzimba. Isetyenziswe ngokubanzi kwi-Hermaceuticals, i-bietechnology, kunye namashishini okutya, kunye nokuveliswa kwemveliso kunye nokutya okusebenzayo ekujoliswe kuwo iMetabolism kunye nempilo yeselula. Kwisimo somzi-mveliso, i-nad inokuveliswa ngokuxutywa, ukusebenzisa i-microorganisosms ukuguqula iimolekyuli zangaphambi kweNad. Inkqubo yemveliso ibandakanya ulawulo ngononophelo lweemeko zokubila zokuphucula ukuguqulwa kwabangaphambi kwe-NAD.
| Into | Ixabiso |
| I-CASS No. | 53-84-9-9 |
| Amanye amagama | I-Beta-Nicotinamide Adenine Didatide |
| MF | C21h27n7O14p2 |
| I-einecs Hayi. | 200-184-4 |
| Indawo yemvelaphi | China |
| Uhlobo | I-Agrochemical Apperpt ephakathi, i-Dyststuff iphakathi, i-flavoundus kunye ne-interpoed Appaep eziPhathisiweyo, izixhobo zokuphila eziphakathi |
| Ubunyulu | I-99% |
| Isicelo | Izinto zokufunda eziphakathi |
| Imbonakalo | Umgubo omhlophe |
| Igama | I-Beta-Nicotinamide Adenine Didatide |
| MW | I-663.43 |
| MF | C21h27n7O14p2 |
| Ifom | Uqinile |
| Imbonakalo | Umgubo omhlophe |
| Moq | I-1kg |
| Iisampulu | Iyafumaneka |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
Ucoceko oluphezulu:I-NAD yethu iveliswa kusetyenziswa iinkqubo zoveliso zokwenza imveliso ukuqinisekisa ukucoceka okuphakamileyo, ukuhlanganisa imigangatho yobuqhetseba efunekayo ekufumaneni amayeza, i-biotechnology, kunye nokusetyenziswa kokutya.
Umgangatho ongaguqukiyo:Sigcina amanyathelo alawula ngayo ngokungqongqo kuyo yonke inkqubo yokuvelisa ukuqinisekisa ukuba iimveliso zethu zeNad zihlala zihlangana ngqo kwinkcazo kunye nemigangatho yokusebenza.
Izicelo eziguquguqukayo:I-Nad yethu inokusetyenziswa kuluhlu olubanzi lwezicelo, kubandakanya i-PARMUCETICALS, izongezo zokutya, ukutya okusebenzayo, kunye neenkqubo zayo ezibalulekileyo, ngenxa yemveliso ebalulekileyo kwi-setabolism kunye nemveliso yamandla.
Ukuthobela umthetho:Iimveliso zethu ze-NAD zinamathela kwimigangatho yolawulo yamanye amazwe, iqinisekisa ukuthotyelwa kwezikhokelo ezifanelekileyo kunye nemigaqo yokhuseleko kunye nomgangatho.
Uncedo oluthembekileyo:Sinamandla okuvelisa kunye nezakhono zokungena ukubonelela ngoncedo oluthembekileyo nolinganayo lwe-NAD ukuze bafezekise iimfuno zabathengi bethu.
Uxhaso lobuchwepheshe:Iqela lethu leengcali linokubonelela ngenkxaso yezobugcisa kunye nesikhokelo ekusebenziseni i-NAD kwizicelo ezahlukeneyo, ukuqinisekisa ukuba abathengi bethu banokukhulisa izibonelelo zeemveliso zethu.
Lilonke, iimveliso zethu ze-NAD ziphawulwa bubunyulu babo obuphezulu, umgangatho ongaguqukiyo, uqwalaselo, ukuthobela ukuthotyelwa, ukubonelelwa ngokuthembekileyo kunye nezicelo ezibanzi zezorhwebo nezorhwebo.
I-β-nicotinamide adenine dieucleotide (i-NAD) ibonelela ngemisebenzi eliqela kunye nezibonelelo zempilo ezinokubandakanya:
Ukuveliswa kwamandla:
I-Nad idlala indima ebalulekileyo ekuvelisweni kwe-adenosine tehosphate (i-ATP), imali yamandla ephambili yeseli. Ngokuthatha inxaxheba kwi-Renox Reactions, i-NAD iququzelela ukudluliselwa kwee-elektroni kwinkqubo ye-phosphory, ebaluleke kakhulu ekuveliseni i-ATP kwi-IPOCHODR.
Imetabolism yeselula:
I-Nad ibandakanyeka kwimilinganiselo eyahlukeneyo ye-metabolic, kubandakanya i-Glykolysis, i-tricarboxyyliccicccid acid (i-TCA), kwaye inamafutha acid ocid. Ezi nkqubo zibalulekile ekuqhekezweni nasekusebenziseni izondlo zemveliso yamandla kunye neselula.
Ukulungiswa kweDNA:
I-Nad yi-enzymes ye-enzymes ebandakanyekayo kwiinkqubo zokulungisa iDNA, ezinjengeepoly (i-adp-ribose) i-polympleses (Parps) kunye ne-studins. Ezi i-enzymes zidlala indima ebalulekileyo ekugcineni uzinzo lwe-gemic kunye nokulungisa umonakalo we-DNA obangelwe ngabacinezeli abahlukeneyo.
Iphasi ibonisa:
I-NAD isebenza njenge-sundociins, iklasi yeeproteni ebandakanyekayo ekulawuleni iinkqubo zeselula ezinjengesifo se-gene, i-Apoptosis, kunye nempendulo yoxinzelelo. I-Soruins ifakwe kwi-longens kwi-ongen kwaye idityaniswe kwizibonelelo zempilo ezinokubakho.
Izibonelelo zempilo ezinokubakho:
Uphando lucebisa ukuba ukungenisa i-NAD OKANYE IMIQATHANGO YAMAHLA ABADALA AMANDLA ABASELULAYO, kubandakanya nokuxhasa umsebenzi we-mitochond, kunye nokuchaphazela okunempilo, kunye noxinzelelo lweselula.
Icocekile β-nicotinamide adenine dieucleotide (i-NAD) inoluhlu lwemizi-mveliso eyahlukeneyo ngenxa yendima yayo ebalulekileyo kwi-Itabolism ye-Itabolism kunye nemveliso yamandla. Ezinye zezinto eziphambili ze-nad i-ned ecocekileyo ibandakanya:
Ishishini lamachiza:
I-NAD isetyenziswa njengecandelo elibalulekileyo kwiindawo ezinokuthintela amayeza ukuphazamiseka kwe-metabolic, i-mitochondIntal ye-mitochondIntal, kunye neemeko ezinxulumene nobudala. Ikwasetyenziswa kuphando kunye nophuhliso longenelelo ngonyango olunokubakho.
Inkxaso-mali yokutya:
I-Nad ifakiwe kwiizongezo zokutya ezijolise ekuxhaseni impilo yeselula, imetabolism ye-metabolism, kunye nentlalontle iyonke. Ezi zongezo zithengiswa ukuba zikho ukuphakamisa ukwaluphala kokwaluphala kunye nomsebenzi we-metabolic.
Ukutya okusebenzayo kunye neZiselo:
I-Nad isetyenziswa kuphuhliso lokutya okusebenzayo kunye neziselo ezenziwe ukuxhasa ukuveliswa kwamandla, impilo yeselula, kunye ne-metabolic. Ezi mveliso zinokujolisa abathengi abafuna iindlela zendalo zokuphucula impilo yabo iyonke kunye namandla.
I-Biotechnology:
I-NAD isebenza kwiinkqubo ezahlukeneyo zebhayoloji, kubandakanya inkcubeko, ukubila kunye nobunjineli be-enzyme. Isebenza njengeyona nto ibaluleke kakhulu kwiindlela ezininzi zokuphendula kwe-enzymatic kunye neMetabolic iindlela, zenza ukuba zibe lixabisekile kwi-bioprocesves kunye nokudilizwa.
Uphando nophuhliso:
I-Nad isetyenziswa njengesixhobo sophando kwilebhu yemfundo nakwimizi-mveliso yokufunda iseti yeselula, imveliso yamandla, kunye nezibonelelo zempilo ezinxulumene nemongokumohlwayo ye-NAD. Ikwangumxholo woPhando lweSayensi ngenxa yeempembelelo zalo zokwaluphala, izifo ze-metabolic, kunye neemeko ze-neurodenegenelitionation.
I-cosmeceuticals:
I-Nad ifakiwe kwimveliso ye-skerecare kunye ne-cosmetic yento enokubakho yokuxhasa impilo yeselula kunye nesondo. Ithengiswa njengesithako ngokuchasene nokwaluphala kunye nokuphindaphindwa kwakhona.
Isicatshulwa sethu sesityalo senziwa sisebenzisa amanyathelo olawulo esemgangathweni kwaye sinamathele kwimigangatho ephezulu yeenkqubo zokuvelisa. Sibeka phambili ukhuseleko kunye nomgangatho wemveliso yethu, ukuqinisekisa ukuba ifezekisa iimfuno zomthetho kunye nezatifikethi zeshishini. Oku kuzinikela kwimigangatho esemgangathweni yokuseka ukuthembana kunye nokuzithemba ekuthembekeni kwemveliso yethu. Inkqubo yemveliso ngokubanzi yile ilandelayo:
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