Ubonelelo ngefektri ecocekileyo i-β-Nicotinamide adenine dinucleotide (NAD)
I-β-Nicotinamide adenine dinucleotide (NAD) yi-coenzyme efumaneka kuzo zonke iiseli eziphilayo, idlala indima ebalulekileyo kwiinkqubo ezahlukeneyo ze-metabolic. Kubalulekile kwimveliso yamandla, ukulungiswa kwe-DNA, kunye nokubonakaliswa kweeseli. I-NAD ikhona ngeendlela ezimbini: i-NAD+ kunye ne-NADH, ezibandakanyekayo kwiimpendulo ze-redox, ukudlulisa ii-electron ngexesha leendlela ze-metabolic. I-NAD ibalulekile ekugcineni umsebenzi weselula kunye nempilo iyonke, kwaye amanqanaba ayo anokuchaphazela iinkqubo ezahlukeneyo zomzimba. Isetyenziswa kakhulu kumayeza, i-biotechnology, kunye namashishini okutya, kunye nokuveliswa kwezongezelelo kunye nokutya okusebenzayo okujolise kumandla e-metabolism kunye nempilo yeselula. Kwimeko yefektri, i-NAD inokuveliswa ngokuvutshelwa, isebenzisa ii-microorganisms ukuguqula iimolekyuli zangaphambili zibe yi-NAD. Inkqubo yemveliso ibandakanya ukulawulwa ngononophelo kweemeko zokuvutshelwa ukuze kuphuculwe uguqulo lwezandulela kwi-NAD.
| Into | Ixabiso |
| Inombolo yeCAS. | 53-84-9 |
| Amanye Amagama | i-beta-Nicotinamide adenine dinucleotide |
| MF | I-C21H27N7O14P2 |
| I-EINECS No. | 200-184-4 |
| Indawo yeMvelaphi | eTshayina |
| Uhlobo | IziPhakathi zeAgrochemical, iziPhakathi zeDyestuff, iziNdawo zeNcasa kunye nevumba eliphakathi |
| Ubunyulu | 99% |
| Isicelo | Idibanisa izinto eziPhambili |
| Imbonakalo | Umgubo omhlophe |
| Igama | i-beta-Nicotinamide adenine dinucleotide |
| MW | 663.43 |
| MF | I-C21H27N7O14P2 |
| Ifom | Iqinile |
| Imbonakalo | Umgubo omhlophe |
| MOQ | 1kg |
| Iisampulu | Iyafumaneka |
| Beka ubomi kwishelufa | iminyaka eyi-2 |
Ukucoceka okuphezulu:I-NAD yethu iveliswa kusetyenziswa iinkqubo eziphucukileyo zokuvelisa ukuqinisekisa ukucoceka okuphezulu, ukuhlangabezana nemigangatho engqongqo yomgangatho ofunekayo kumayeza, i-biotechnology, kunye nokusetyenziswa kokutya.
Umgangatho ohambelanayo:Sigcina imilinganiselo engqongqo yolawulo lomgangatho kuyo yonke inkqubo yemveliso ukuqinisekisa ukuba iimveliso zethu ze-NAD zihlala zihlangabezana neenkcukacha ezifunekayo kunye nemigangatho yokusebenza.
Ii-Aplikeshini eziNyezo:I-NAD yethu ingasetyenziswa kuluhlu olubanzi lwezicelo, kubandakanya amayeza, izongezo zokutya, ukutya okusebenzayo, kunye neenkqubo ze-biotechnological, ngenxa yendima yayo ebalulekileyo kwimetabolism yeselula kunye nokuveliswa kwamandla.
Ukuthotyelwa koMgaqo:Iimveliso zethu ze-NAD zihambelana nemigangatho yolawulo yamazwe ngamazwe, ziqinisekisa ukuthotyelwa kwemigaqo efanelekileyo kunye nemimiselo yokhuseleko kunye nomgangatho.
Unikezelo oluthembekileyo:Sinomthamo wemveliso kunye nobuchule bokulungiselela ukubonelela ngobonelelo oluthembekileyo noluzinzileyo lwe-NAD ukuhlangabezana neemfuno zabathengi bethu.
Uxhaso lobuchwepheshe:Iqela lethu leengcali linokubonelela ngenkxaso yobugcisa kunye nesikhokelo ekusebenziseni i-NAD kwizicelo ezahlukeneyo, ukuqinisekisa ukuba abathengi bethu banokwandisa inzuzo yeemveliso zethu.
Ngokubanzi, iimveliso zethu ze-NAD ziphawulwa kukucoceka kwazo okuphezulu, umgangatho ongaguquguqukiyo, uguquguquko, ukuthotyelwa kwemithetho, unikezelo oluthembekileyo, kunye nenkxaso ebanzi yobuchwephesha, ezenza zilungele usetyenziso olwahlukeneyo lwemizi-mveliso nezorhwebo.
I-β-Nicotinamide adenine dinucleotide (NAD) ecocekileyo ibonelela ngemisebenzi emininzi kunye neenzuzo zempilo ezinokubakho, kubandakanya:
Ukuveliswa kwamandla:
I-NAD idlala indima ebalulekileyo ekuvelisweni kwe-adenosine triphosphate (ATP), eyona mali iphambili yamandla kwiseli. Ngokuthatha inxaxheba kwi-redox reactions, i-NAD iququzelela ukuhanjiswa kwee-electron kwinkqubo ye-phosphorylation ye-oxidative, ebalulekileyo ekuveliseni i-ATP kwi-mitochondria.
IMetabolism yeSelula:
I-NAD ibandakanyeka kwiindlela ezahlukeneyo ze-metabolic, kubandakanya i-glycolysis, umjikelezo we-tricarboxylic acid (TCA), kunye ne-fatty acid oxidation. Ezi nkqubo zisisiseko sokuqhekeka kunye nokusetyenziswa kwezondlo zokuvelisa amandla kunye nokusebenza kweeseli.
Ukulungiswa kweDNA:
I-NAD yi-co-substrate yee-enzyme ezibandakanyekayo kwiinkqubo zokulungisa i-DNA, njenge-poly (ADP-ribose) i-polymerases (PARPs) kunye ne-sirtuins. Ezi enzymes zidlala indima ebalulekileyo ekugcineni ukuzinza kwe-genomic kunye nokulungisa umonakalo we-DNA obangelwa zixinzelelo ezahlukeneyo.
Umqondiso weSeli:
I-NAD isebenza njenge-substrate ye-sirtuins, iklasi yeeprotheni ezibandakanyekayo ekulawuleni iinkqubo zeselula ezifana ne-gene expression, i-apoptosis, kunye nokuphendula koxinzelelo. I-Sirtuins ibandakanyeka kubomi obude kwaye idibaniswe neenzuzo zempilo ezinokuthi zibekho.
Uncedo lweMpilo olunokubakho:
Uphando lucebisa ukuba ukongezwa kwe-NAD okanye ukumodareyithwa kwamanqanaba e-NAD kunokuba neenzuzo zempilo ezinokubakho, kubandakanya ukuxhasa umsebenzi we-mitochondrial, ukukhuthaza ukwaluphala okunempilo, kunye neemeko ezinokuthi zibe neempembelelo ezinxulumene nokungasebenzi kakuhle kwe-metabolic kunye noxinzelelo lweselula.
I-β-Nicotinamide adenine dinucleotide (NAD) ecocekileyo inoluhlu lwezicelo kuwo wonke amashishini ahlukeneyo ngenxa yendima yayo ebalulekileyo kwimetabolism yeselula kunye nokuveliswa kwamandla. Ezinye zezicelo eziphambili ze-NAD ecocekileyo ziquka:
Umzi mveliso wamachiza:
I-NAD isetyenziswe njengenxalenye ebalulekileyo ekuqulunqweni kwamachiza, ngokukodwa kumayeza ajolise ukuphazamiseka kwe-metabolic, ukungasebenzi kwe-mitochondrial, kunye neemeko ezinxulumene neminyaka. Ikwasetyenziswa kuphando nakuphuhliso longenelelo olunokubakho lonyango.
Izongezo zokutya:
I-NAD ibandakanyiwe kwizongezo zokutya ezijolise ekuxhaseni impilo yeselula, i-metabolism yamandla, kunye nempilo yonke. Ezi zongezo zithengiselwa amandla azo okukhuthaza ukwaluphala okunempilo kunye nokusebenza kwemetabolism.
Ukutya okuSebenzayo kunye neziselo:
I-NAD isetyenziswa kuphuhliso lokutya okusebenzayo kunye neziselo eziyilelwe ukuxhasa imveliso yamandla, impilo yeselula, kunye nokulungelelana kwe-metabolic. Ezi mveliso zinokujolisa kubathengi abafuna iindlela zendalo zokuphucula impilo kunye namandla abo.
I-Biotechnology:
I-NAD iqeshwe kwiinkqubo ezahlukeneyo ze-biotechnological, kuquka inkcubeko yeeseli, ukuvutshelwa, kunye nobunjineli be-enzyme. Isebenza njenge-cofactor ebalulekileyo kwiimpendulo ezininzi ze-enzymatic kunye neendlela ze-metabolic, iyenza ixabiseke kwi-bioprocessing kunye ne-biomanufacturing.
Uphando nophuhliso:
I-NAD isetyenziswa njengesixhobo sophando kwiilabhoratri zemfundo kunye nezoshishino ukufunda i-metabolism yeselula, ukuveliswa kwamandla, kunye neenzuzo zempilo ezinokubakho ezinxulumene nokumodareyitha kwe-NAD. Ikwangumxholo wophando lwezenzululwazi ngeziphumo zawo ekwaluphaleni, izifo ze-metabolic, kunye neemeko ze-neurodeergenerative.
Izinto zokuthambisa:
I-NAD ibandakanyiwe kwi-skincare kunye neemveliso zokuthambisa ukuze ikwazi ukuxhasa impilo yeselula kunye namandla. Ithengiswa njengesithako esichasene nokuguga kunye neempawu zokuvuselela.
I-Extract yethu esekwe kwiZityalo yenziwa kusetyenziswa amanyathelo angqongqo okulawula umgangatho kwaye ithobela imigangatho ephezulu yeenkqubo zemveliso. Sibeka phambili ukhuseleko kunye nomgangatho wemveliso yethu, siqinisekisa ukuba iyahlangabezana neemfuno zolawulo kunye neziqinisekiso zeshishini. Oku kuzibophelela kumgangatho kujolise ekusekeni intembeko kunye nokuzithemba ekuthembekeni kwemveliso yethu. Inkqubo yemveliso jikelele ngolu hlobo lulandelayo:
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Umnyango ukuya emnyango inkonzo lula ukuthatha iimpahla
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