I-Camptotheca Acuminata Extract
I-Camptotheca acuminata extractluhlobo oluxineneyo lwe-camptothecin edityanisiweyo, ephuma kwixolo kunye namagqabi omthi we-Camptotheca acuminata. Isicatshulwa sicutshungulwa ukuze siqulathe umgubo we-camptothecin ococekileyo ongama-98% min.ICamptothecinyi-alkaloid yendalo ebonakalise iimpawu ezithembisayo zokulwa nomhlaza. Isebenza ngokuthintela umsebenzi we-enzyme i-topoisomerase, ebandakanyeka ekuphindaphindweni kwe-DNA kunye nokwahlulahlula iiseli. Uphando lubonise ukuba i-camptothecin inokujolisa kwaye ibulale iiseli zomhlaza ngempumelelo. Ke ngoko, isicatshulwa sihlala sisetyenziswa kuphuhliso lwamayeza e-chemotherapy kunye nolunye unyango lwamayeza kwiintlobo ezahlukeneyo zomhlaza. Nangona kunjalo, kubalulekile ukuqaphela ukuba i-camptothecin yikhompawundi enamandla kwaye kufuneka isetyenziswe kuphela phantsi kweliso kunye nesikhokelo seengcali zonyango.
| Igama lemveliso | ICamptothecin | Beka ubomi kwishelufa | iminyaka eyi-2 |
| Icandelo Elisetyenzisiweyo | ingcambu | Inkangeleko | umgubo ocolekileyo otyheli okhanyayo |
| Inkcazo | 98% | ||
| Indawo yokugcina izinto | Gcina kwisikhongozeli esivalwe kakuhle kude nomswakama kunye nelanga elithe ngqo | ||
| Beka ubomi kwishelufa | Iinyanga ezingama-36 ukuba zivaliwe kwaye zigcinwe kakuhle | ||
| Indlela yokubulala iintsholongwane | Ishushu kakhulu, ayitshisi. | ||
| Into | Inkcazo | Iziphumo zovavanyo |
| Ulawulo Lomzimba | ||
| Inkangeleko | umgubo opinki okhanyayo | Ukuhambelana |
| Ivumba elibi | Uphawu | Ukuhambelana |
| Incasa | Uphawu | Ukuhambelana |
| Icandelo Elisetyenzisiweyo | hamba | Ukuhambelana |
| Ilahleko xa komiswa | ≤5.0% | Ukuhambelana |
| Uthuthu | ≤5.0% | Ukuhambelana |
| Indlela yoMveliso | Ukukhupha i-CO2 ebaluleke kakhulu | Ukuhambelana |
| Ii-allergens | Akukho nanye | Ukuhambelana |
| Ulawulo lweeKhemikhali | ||
| Iintsimbi ezinzima | I-NMT 10ppm | Ukuhambelana |
| I-Arsenic | I-NMT 2ppm | Ukuhambelana |
| Inkokeli | I-NMT 2ppm | Ukuhambelana |
| I-Cadmium | I-NMT 2ppm | Ukuhambelana |
| I-Mercury | I-NMT 2ppm | Ukuhambelana |
| Imeko ye-GMO | Ayina-GMO | Ukuhambelana |
| Ulawulo lweMikrobiyoloji | ||
| Inani Lilonke Leepleyiti | 10,000cfu/g Ubuninzi | Ukuhambelana |
| Imvubelo kunye noMngundo | 1,000cfu/g Ubuninzi | Ukuhambelana |
| E.Coli | Okungalunganga | Okungalunganga |
| I-Salmonella | Okungalunganga | Okungalunganga |
(1)Uxinzelelo oluphezulu:Iqulethe i-98% ye-camptothecin powder ecocekileyo.
(2)Imvelaphi yendalo:Ithathwe kwiCamptotheca acuminata, umthi odalelwe eTshayina.
(3)Iimpawu zokulwa nomhlaza:ICamptothecin ibonakalise ukuba inamandla okulwa nomhlaza.
(4)Ikhompawundi ye-chemotherapy:Isetyenziswa kunyango lomhlaza olujoliswe kulo.
(5)Iarhente enamandla yokulwa nomhlaza:Isebenza kakuhle ekuthinteleni ukukhula kweethumba.
(6)Ikhuthaza ukufa kweeseli zomhlaza:Ibangela i-apoptosis kwiiseli zomhlaza.
(7)Enye indlela yonyango lwesintu:Ibonelela ngendlela yendalo yonyango lomhlaza.
(8)Imveliso yendalo enokuthi ilwe nomhlaza:Icingelwa uphando olongezelelekileyo kunye nophuhliso.
(9)I-antioxidant enamandla:Inceda ukulwa noxinzelelo lwe-oxidative kwaye inciphisa umonakalo weeseli.
(10)Ukhuseleko kunye noqinisekiso lomgangatho:Yenziwe phantsi kwemigangatho engqongqo yolawulo lomgangatho.
(1) Iimpawu zokulwa nomhlaza:I-Camptothecin, eyona nto iphambili esebenzayo kwi-camptotheca acuminata extract, ibonakalise umsebenzi othembisayo wokulwa nomhlaza kwizifundo zangaphambi kweklinikhi. Ithintela i-enzyme i-topoisomerase I, ebandakanyeka ekuphindaphindweni nasekubhalweni kwe-DNA, ekugqibeleni ikhokelela ekuthintelweni kokukhula kweeseli zomhlaza.
(2) Umsebenzi we-Antioxidant:Kufunyenwe ukuba i-Camptotheca acuminata extract inomsebenzi we-antioxidant, onceda ekunciphiseni ii-free radicals eziyingozi emzimbeni. Ii-antioxidants zinokuba negalelo kwimpilo iyonke ngokukhusela iiseli kumonakalo obangelwa luxinzelelo lwe-oxidative.
(3) Iziphumo zokulwa nokuvuvukala:Ezinye izifundo zibonise ukuba i-camptotheca acuminata extract inokuba neempawu zokulwa nokuvuvukala. Ukudumba kunxulunyaniswa nezifo ezahlukeneyo ezingapheliyo, kwaye ukunciphisa ukudumba kunokuba nefuthe elihle kwimpilo iyonke.
(4) Umsebenzi wokulwa neentsholongwane:Uphando lokuqala lubonise ukuba i-camptotheca acuminata extract, ingakumbi i-camptothecin, inokubonakalisa iimpawu zokulwa neentsholongwane. Ibonakalise iziphumo zokuthintela iintsholongwane ezithile, kuquka i-herpes simplex virus kunye ne-human cytomegalovirus.
(1) I-Camptotheca acuminata extract isetyenziswa kakhulu kwiamayeza emveli aseTshayinangenxa yeempawu zayo zokulwa nomhlaza.
(2) Iqulethe i-camptothecin, ikhompawundi yendalo ethintelaukuphindaphinda kweeseli zomhlaza.
(3) Isetyenziswe kwiunyango lwekhemotherapikwiintlobo ezithile zomhlaza, kuquka umhlaza wemiphunga, wesibeleko, kunye nomhlaza we-colorectal.
(4) Ikwabonakalise amandla okunyangaiithumba zobuchopho kunye ne-leukemia.
(5) Isicatshulwa sineempawu ze-antioxidant kwaye sinokuncedakhusela kuxinzelelo lwe-oxidative kunye nomonakalo we-DNA.
(6) Izifundo zibonise ukuba i-Camptotheca acuminata extract inokuba nefuthe lokulwa nokuvuvukala, nto leyo eyenza ukuba ibe luncedo kwiimeko ezifanaisifo samathambo kunye nesifo samathumbu esivuthayo.
(7) Ikwaphandwa malunga nobuchule bayo kwiunyango lwe-HIV kunye ne-hepatitis.
(8) Isetyenziswa kwiiimveliso zokhathalelo lolusungenxa yamandla ayo okukhuthaza ukuveliswa kwe-collagen kunye nokuphucula ukuthamba kolusu.
(9) Ibisoloko isetyenziswa ngokwesikoiipropati zayo zokuthomalalisa iintlungu.
(10) Esi sicatshulwa sisasetyenziswa kakhulu kuphando, kwaye kufuneka uphando olongezelelweyo ukuze kuhlolwe amandla aso kwiindlela ezahlukeneyo zonyango.
(1) Ukuvuna:Isityalo seCamptotheca acuminata sivunwa kwinqanaba elifanelekileyo xa umxholo weCamptothecin uphezulu.
(2) Ukomisa:Izinto ezivuniweyo zesityalo zomiswa kusetyenziswa indlela efanelekileyo, njengokomisa ngomoya okanye ukomisa ngoncedo lobushushu.
(3) Ukusila:Izinto zesityalo ezomileyo zicolwa kakuhle zibe ngumgubo kusetyenziswa izixhobo zokusila.
(4) Ukukhupha:Umgubo ocoliweyo ufakwa kwinkqubo yokukhupha kusetyenziswa isinyibilikisi esifanelekileyo, esidla ngokuba yindibaniselwano yamanzi kunye nezinyibilikisi zendalo.
(5) Ukuhluza:Isisombululo esikhutshiweyo siyahluzwa ukuze kususwe naluphi na ukungcola okuqinileyo okanye iintsalela zezityalo.
(6) Ukugxila:Isisombululo esihluziweyo sixutywe phantsi koxinzelelo oluphantsi okanye ngokuyikhupha i-solvent ukuze kwandiswe uxinzelelo lwe-camptothecin.
(7) Ukuhlanjululwa:Iindlela zokucoca ezongezelelweyo, ezinje nge-chromatography, i-crystallization, okanye i-solvent partitioning, zingasetyenziswa ukwahlula nokucoca i-camptothecin.
(8) Ukomisa:I-camptothecin ecociweyo iyomiswa ukuze kususwe naluphi na umswakama oseleyo.
(9) Ukusila:I-camtothecin eyomileyo iyasilwa ukuze kufunyanwe imo yomgubo ocoliweyo.
(10) Ulawulo loMgangatho:Imveliso yokugqibela ivavanywa ngobuchule ukuqinisekisa ukuba iyahlangabezana neemfuno ezifunekayo ze-98% ye-camptothecin.
(11) Ukupakisha:Umgubo we-camptothecin ophumayo oyi-98% upakishwa kwizikhongozeli ezifanelekileyo, ulungele ukusasazwa okanye ukusetyenzwa ngakumbi.
Indawo yokugcina: Gcina kwindawo epholileyo, eyomileyo, necocekileyo, Khusela ukufuma kunye nokukhanya okuthe ngqo.
Iphakheji enkulu: 25kg/idrama.
Ixesha lokuKhokhela: Iintsuku ezisi-7 emva kweodolo yakho.
Ubomi beShelufu: Iminyaka emi-2.
Phawula: Iinkcukacha ezenziwe ngokwezifiso nazo zinokufezekiswa.
Express
Ngaphantsi kwe-100kg, iintsuku ezi-3-5
Inkonzo yokungena emnyango kulula ukuyithatha impahla
Ngaselwandle
Ngaphezulu kwe-300kg, malunga neentsuku ezingama-30
Kufuneka umthengisi weenkonzo zokucoca iinqanawa ukusuka kwelinye izibuko ukuya kwelinye
Ngomoya
100kg-1000kg, iintsuku ezi-5-7
Kufuneka umthengisi weenkonzo zokucoca izikhululo zeenqwelo-moya ukusuka kwisikhululo seenqwelo-moya ukuya kwisikhululo seenqwelo-moya
I-Camptotheca Acuminata Extractiqinisekiswe ngesatifikethi se-ISO, isatifikethi se-HALAL, kunye nesatifikethi se-KOSHER.
Isicaphucaphu nokuhlanza: I-Camptothecin ngokwayo inokubangela ukuphazamiseka kwamathumbu, kuquka isicaphucaphu nokuhlanza. Ezi ziphumo bezingalindelekanga zinokulawulwa ngamayeza okulwa nokugabha.
Urhudo:I-Diarrhea yenye imiphumo eqhelekileyo ye-camptothecin. Umthamo owaneleyo kunye namayeza afanelekileyo okulwa ne-diarrhea kunokufuneka ukulawula le miphumo.
Ukunciphisa i-Myelosuppression:I-Camptothecin inokucinezela umongo wethambo kwaye ichaphazele ukuveliswa kweeseli zegazi, nto leyo ekhokelela ekunciphiseni kweeseli zegazi ezibomvu nezimhlophe kunye neeplatelets. Oku kunokubangela i-anemia, ukwanda kokuchaphazeleka zizifo, kunye nomngcipheko wokopha. Uvavanyo lwegazi rhoqo luyafuneka ukuze kujongwe inani leeseli zegazi ngexesha lonyango.
Ukudinwa:Ukudinwa sisiphumo esiqhelekileyo seziyobisi ezininzi ze-chemotherapy, kuquka i-camptothecin. Kubalulekile ukuphumla nokonga amandla ngexesha lonyango.
Ukulahleka kweenwele:I-Camptothecin inokubangela ukulahleka kweenwele, kuquka iinwele zentloko, zomzimba, nezobuso.
Umngcipheko wosulelo:I-Camptothecin inokwenza buthathaka amajoni omzimba, yonyuse umngcipheko wokosuleleka. Kubalulekile ukuthatha amanyathelo okuthintela umngcipheko wokosuleleka ziintsholongwane ngexesha lonyango.
Iimpendulo ze-allergy:Abanye abantu banokuba neempembelelo ze-allergic kwi-camptotheca acuminata extract. Iimpawu zingaqala kwezincinci ukuya kwezinzima kwaye zinokubandakanya ukurhawuzelela, ukurhawuzelela, ukuphefumla okufutshane, kunye nokudumba. Kufuneka kufunwe uncedo lwezonyango ngokukhawuleza xa kukho impendulo ye-allergic enzima.
Ubuthi besibindi:I-Camptothecin inokubangela ubuthi besibindi, nto leyo ekhokelela kwii-enzymes zesibindi eziphezulu kunye nomonakalo onokwenzeka kwisibindi. Uvavanyo lokusebenza kwesibindi kufuneka lujongwe rhoqo ngexesha lonyango.
Iimpendulo ze-Hypersensitivity:Amaxesha amaninzi, abantu banokufumana iimpendulo ze-hypersensitivity kwi-camptothecin, ezinokuquka iimpawu ezinje ngomkhuhlane, ukugodola, kunye nobunzima bokuphefumla. Kufuneka kufunwe uncedo lwezonyango ngokukhawuleza ukuba ezi mpawu ziyenzeka.
Kubalulekile ukuxoxa ngazo naziphi na iziphumo ebezingalindelekanga kunye namanyathelo okhuseleko nogqirha ngaphambi kokuba uqalise naluphi na unyango nge-camptotheca acuminata extract. Banokubonelela ngeengcebiso ezilungiselelwe wena ngokusekelwe kwimbali yezonyango yomntu ngamnye kunye nendlela ethile yokwenziwa kwe-extract esetyenziswayo.
