Intshayelelo
GinsenossidesNgaba iklasi yeMigaqo yeNdalo efumaneka kwiingcambu zePanax Ginseng River, esele isetyenziselwe iinkulungwane kumayeza e-China. Ezi ngqingqiweyo ze-bioudies ziye zaqwalaselwa kakhulu kule minyaka idlulileyo ngenxa yezibonelelo zempilo ezinokubakho. Kweli nqaku, siza kuphonononga izibonelelo ezahlukeneyo ze-geinsenosside, kubandakanya neziphumo zabo zomsebenzi wengqondo, imodyuli yendlela yokusebenza komzimba, i-anti-inforatory, kunye nomsebenzi onokubakho.
Umsebenzi wengqondo
Enye yezona njongo zaziwayo ze-rinsenossides kukuphucula ukusebenza kwengqondo. Izifundo ezininzi zibonakalisile ukuba i-geninossides inokuphucula inkumbulo, ukufunda kunye nokusebenza kwengqondo ngokupheleleyo. Ezi ziphumo zicingelwa ukuba zinqunywe ngeendlela ezahlukeneyo, kubandakanya nemo yokucotha, njenge-acetylcholine kunye ne-dogamine, kunye nokukhuthaza i-neurogenesis, inkqubo yokuvelisa ii-neurons ezintsha kwingqondo.
Kwisifundo esipapashwe kwijenali ye-EntenoPophant, abaphandi bafumanisa ukuba i-gensenossides inokuphucula ukufunda kwendawo ene-neurostrophic (i-BDNF), iproteni exhasa ukusinda nokukhula kwee-neurons. Ukongeza, i-gensenosides ibonisiwe ukukhusela ukuhla kwengqondo yengqondo kunye nezifo ze-neurodegenege, ezinje nge-alzheimer's kunye ne-aldinson, ngokunciphisa uxinzelelo lwe-oxidatives kunye nokuvuvukala kwingqondo.
Ukungasebenzi kakuhle
I-gensenosides ifunyenwe ifunyazwe ukuba inyanzelise amajoni omzimba, ephucula amandla ayo okuzikhusela kusulelo nakwizifo. Ezi qubwo zibonakalisiwe ukukhuthaza imveliso kunye nomsebenzi weseli eyahlukeneyo yokhuselo, ezinje ngeeseli zokubulala, iiseli ezifana ne-MACROSE, kunye neTymphocyte, edlala indima ebalulekileyo ekuzikhuseleni komzimba kunye neeseli zomhlaza.
Uphononongo olupapashwe kwijenali yeHlabathi yeHlabathi ibonakalise ukuba i-gensenossides inokuphucula impendulo yomzimba kwi-MICE ngokwandisa ukuveliswa kwemisebenzi ye-cytoke. Ngapha koko, i-gensenossides ibonisiwe ukuba ineepropathi zentsholongwane kunye nentsholongwane, ibenza ukuba babe lumenzisa unyango lwempilo yokuxhasa amajoni omzimba kunye nokuthintela usulelo.
Iipropathi ze-anti-insulmatory
Ukuvuvukala yimpendulo yendalo yamajoni omzimba okulimala ekomelezelweni nasekusuleleni izifo ezinokuba negalelo kuphuhliso lwezifo ezahlukeneyo, kubandakanya isifo sentliziyo, isifo sentliziyo, kunye nomhlaza. I-ginsenosides ifunyenwe ukuba inepropathi enokubakho e-anti-insulmatory, enokunceda ukunciphisa imiphumo eyingozi yokuphelisa ukunganyangekiyo emzimbeni.
Uphando olupapashwe kwijenali yoPhando lukaGinseng kubonise ukuba i-rinsenossides inokucinezela ukuveliswa kwe-cystokines ye-pro-insulmatory kwaye ithintele ukusebenza kwe-evormays. Ukongeza, i-gensenosides ibonisiwe ukunciphisa ukubonakaliswa kwee-Demolmators, ezinjenge-cybooxygesege-2 (i-Cox-2) kunye ne-witric i-witric synthase (i-Inos), ebandakanyekayo kwimpendulo ye-inflommatory.
Umsebenzi we-anticerr
Enye inkalo yomdla kuPinanodeded pheshelo ngumsebenzi wabo wokulwa. Izifundo ezininzi ziye zacebisa ukuba i-binsenossides ingenzi iziphumo ezichasene nomhlaza ngokuthintela ukukhula kunye nokwanda kweeseli zomhlaza), kwaye icinezelele i-turus enguogenesis (ukunyanzelisa imithambo yegazi).
Uphengululo olupapashwe kwijenali yehlabathi yezimoya zemolekyuli igxininise ukubakho kwe-anticialr ye-gensenossides, ngakumbi esifubeni, imiphunga, kunye nomhlaza we-cemared. Uphengululo luxoxa ngeendlela ezahlukeneyo apho i-gensenosses isebenza khona Iziphumo zabo zokulwa umhlaza, kubandakanya nemo yokuhambisa iiseli, ummiselo wendlela yokuphendula yomzimba, kunye nokuphuculwa kwempendulo yomhlaza.
Ukuqukumbela
Ukuqukumbela, i-gensenossides ziikhonkrithi zeBioudive ezifumaneka kwiPanax Ginseng enikezela uluhlu olubanzi lwezibonelelo zempilo ezinokubakho. Oku kubandakanya ukuphuculwa komsebenzi wokuqonda, imodyuli yenkqubo yokuzikhusela, i-anti-insulmatory, kunye nomsebenzi we-anticesr onokubakho. Ngelixa kufuna uphando olungakumbi ukuze uqonde ngokupheleleyo iindlela zentshukumo kunye nonyango lwe-gensenososides, ubungqina obukhoyo zibonisa ukuba ezi zikhombisi zithembisa njengezixhobo zendalo zokukhuthaza impilo-ntle yendalo yokukhuthaza impilo nentlalontle yendalo.
Izalathiso
Kim, JH, & Yi, ys (2013). I-Ginsenotid RG1 icinezela ukwenza iiseli ze-Dendritic kunye ne-T selfelferation kwiVitro naseVivo. I-Interphecology yeHlabathi, 17 (3), 355-362.
I-Leung, kw, neWng, njengoko (2010). I-pharmacology ye-ginsenossides: uphononongo loncwadi. Amayeza amaTshayina, 5 (1), 20.
I-radad, k., gille, g., liu, l., i-rausch, i-WD, kunye nokusebenzisa i-Ginseng kwiMedicanced kugxininise kuphazamiseka kwe-neurodegenege. Ijenali yeSayensi yezeNqadi, i-100 (3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, isicwangciso esinokubakho se-neuroproproceting. Uhlobo olusekwe kubungqina kunye nelinye iyeza, 2012.
Yun, tk (2001). Ukuqaliswa ngokutsha kwePanax Ginseng cayer. Ijenali yeSayensi yezoNyango yaseKorea, i-16 (SOPL), S3.
Iposi: Apr-16 ukuya ku-2424
