Iindaba - Ngaba ilayisensi i-Glabridin isebenza ngokwenene?

Intshayelelo

Umzi-mveliso wokhathalelo ulusu luyekile ukubetha kwemhlophe "Glabriddin"(Ikhutshiwe kwi-Glycyrrrhiza Glabra) njengoko idlula inkokeli ye-whiteling arbutin ngokutsiba ama-1164, ifumana isihloko segama elithi" Ngaba ifezekisile njani imiphumo engaqhelekanga?

Njengoko amaxesha atshintshayo kwaye izitrato zihonjiswe ngemilenze "engenanto yayo kunye neengalo zencoko phakathi kokuzikhusela kwelanga, ngokungakhathali kuluhlaza okomhlophe.

Kwindawo yokhathalelo lolusu, izithako ezimhlophe zininzi, kubandakanya iVitamin C, i-Niacinamide, i-Arbutin, i-hinexaamic acid, fenexaamic acid, fenethylresorkol (377), nangaphezulu. Nangona kunjalo, i-glabridy "i-Glabridin" inomdla wabalandeli abaninzi, ikhuthaze ukuhlola okunzulu ukutyhila ukuthandwa kwayo. Masiphathe kwiinkcukacha!

Ngalesi sivakalisi, sijonge ukulungisa ezi ngongoma ziphambili zilandelayo:
(1) Imvelaphi ye-Glabridin? Inxibelelana njani "ne-Glycyrrrrrrshiza yeGlabra"?
(2) Kutheni "uGlabridin" ehlonitshwa njengegolide "emhlophe"?
(3) Zeziphi izibonelelo ze "glabriddin"?
(4) I-Glabridlin ifikelela njani imiphumo yayo emhlophe?
(5) Ngaba ilayisensi inene inokwenzeka njengamaqhinga?
(6) Zeziphi iimveliso zononophelo lwesikhumba?

Hayi.1 ndiphefumlela imvelaphi ye "Glariddin"

I-Glariddin, ilungu lentsapho ye-Ilaricoid, ithathwa kwisityalo "glycyrrrrshiza glabra." Kwilizwe lam, kukho iintlobo ezisibhozo eziphambili zelayisensi, ezinamaphepha-ntlobo ezintathu ezibandakanyiwe kwi "Pharmacovia," engu-I-IURORORII I-XE I-CLAGE, kunye ne-Clarice Glabra. I-Glycyrthhize ifumaneka ngokukodwa e-Glycyrrrhiza i-Glabra, esebenza njengeyona nto iphambili ye-IROOFAOFAVODOON yesityalo.

Ifomula yesakhiwo se-glycyrthrizin
Ekuqaleni kufunyenwe yinkampani yaseJapan isuswe i-ruzen kwaye ikhutshwe kwi-Glycyrrrshiza eGlabra, i-Glycyrrrhize isetyenziswa ngokubanzi njengemveliso yemvelaphi yolusu kwi-japan, iKorea, kunye neempawu ezahlukeneyo zolusu. Nangona kunjalo, kubalulekile ukuba uqaphele ukuba isithako esidweliswe kwiimveliso ze-skercare esiyisebenzisayo asinakuba yi "glycyrrrrizen" kodwa "i-Glycyrrrrrrshiza." Ngelixa "i-glycyrrizin" yinto enye, "inokubandakanya izinto ezongeziweyo ezingazange zibodwa kwaye zisebenza njengezimpawu zentengiso" zendalo ".

HA.2 Kutheni ilayisensi ibizwa ngokuba "yigolide emhlophe"?

I-Glycyrthrizin sisithako esinqabileyo nesicelomngeni sokukhupha. I-Glycyrrshiza yeGlabra ayifumaneki ngokulula. Zidityaniswe nobunzima benkqubo yokukhupha, ingaphantsi kwe-100 yeegrem ezinokufumaneka kwitoni enye ye-intanethi kunye namagqabi. Oku kunqothusa kuqhuba ixabiso layo, kuyenza yenye yezona zinto zimbi kakhulu kwiimveliso ze-skerecare, ezithelekiswa negolide. Ixabiso lezinto ezingama-90% ezimsulwa zale mixholo ye-surement ukuya kwi-200,000 yuan / kg.
Ndamangaliswa, ke ndityelele iwebhusayithi yeAladdin ukuqinisekisa iinkcukacha. I-chaltity ecocekileyo (ubunyulu ≥99%) i-lipice inikezelwa kwixabiso lentengiso le-780 yuan / 20mg, ilingana ne-39,000 yuan / g.
Ngephanyazo, ndafumana intlonipho entsha kwesi sithako esingaqhelekanga. Iziphumo zayo ezingenamlilo ze-whitering ziyifumene ngokufanelekileyo isihloko se "Gold" yegolide "okanye" i-whitener yegolide ".

Hayi .. Uyintoni umsebenzi we-Glabridin?

I-Glabridin inobuninzi beepropathi zebhayoloji. Isebenza njengendawo efanelekileyo, ekhuselekileyo nenobuhlobo obufundisileyo kwindalo emhlophe kunye nokususwa kwe-freckle. Ukongeza, inayo i-antibacterial, i-anti-insulmatory, i-antioCxidant, i-anti-alraing, kunye neziphumo. I-Hoitien ebonakalayo, ukuqaqambisa, kwaye ukususwa kwe-freckle kuxhaswa yidatha yovavanyo, etyhila isiphumo se-vitamin C ngaphaya kwamaxesha ali-16, kunye ne-arhente yodumo edumileyo.

Hayi.4 Yintoni eyona ndlela imhlophe?

Xa ulusu luvezwa yimisebe ye-ultraviolet, inkwantyile ukuveliswa kweeradicals zasimahla, ii-melanocytes ziyashukunyiswa ukuba zivelise i-tyrosinase. Ngaphantsi kwempembelelo yale i-enzyme, i-tsrosine kulusu livelisa i-lanin, ekhokelela kulusu olumnyama njengoko i-mpumanin ithuthwe ukusuka kwisiseko se-stratum.
Umgaqo osisiseko waso nasiphi na isithako esimhlophe kukungenelela kwinkqubo yokuqulunqwa kweMelanin okanye ukuthutha. I-Glabridin yeMfilinya kaGlabriddin ngokuyintloko idibanisa ezi zinto zintathu zilandelayo:
(1) ethintele umsebenzi weTyrosinase
I-Glabridin ibonisa ifuthe lokuthintela i-tyrosidase yomsebenzi, ukuvelisa iziphumo ezicacileyo nezibalulekileyo. Ukuphononongwa kwekhompyuter kutyhila ukuba i-Glabridin ingabophelela kwiziko elisebenzayo le-tydrogen kwimveliso ye-hydrogen, ivimba ngokufanelekileyo iMveliso ye-Melanin (i-tyrosine), emva koko inyanzelisile imveliso ye-zulanin. Le ndlela, eyaziwa ngokuba yi-inhibition yokhuphiswano, i-akin kwisenzo sothando esinzulu.

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Ukuvezwa kwe-iltraviolet rays iqulathe imveliso yeentlobo zeoksijini (i-radicals yasimahla), enokwenzakalisa i-phospholipid ye-phospholipid yolusu, ekhokelela kwi-erythema kunye ne-ramemation. Yiyo loo nto, iindidi ezisebenzayo ze-OXGNGN ziyaziwa ukuba negalelo kulusu lwesikhumba, zigxininisa ukubaluleka kokukhuliswa kwelanga kwi-skercare. Izifundo zovavanyo zibonakalise ukuba i-Glabridn ibonise amandla afanayo angenakuthelekiswa nangokungacacanga kwi-Superoxide (SOD), ukusebenza njenge-antioxidant. Oku kusebenza ukunciphisa izinto ezinegalelo kwi-tyrosinase eyongezelelweyo.

(3) Ukuthintela ukuvuvukala
Ukulandela umonakalo wesikhumba kwi-Ultraviolet, imbonakalo ye-erythema kunye ne-pigmentation ihamba kunye nokuvuvukala, ukuqhubela phambili ukuvelisa imveliso ye-melanin kunye nokuphakamisa umjikelo owonakalisayo. Iipropathi zikaGlabridin Anti-I-EndolmaridMatory Yenza imeko efanelekileyo yokuthintela umkhondo we-melanin ukuya kwinqanaba elithile, ngelixa ikhuthaza ukulungiswa kolusu olonakeleyo.

No. 5 Ngaba iqhina elinamandla?

I-Glabridin ichithwe njengesithako esisebenzayo nesiyisingqongileyo esiyingqongileyo yeWhitenation kunye nokususwa kwe-freckle, ukuqhwanyaza kwenkqubo yemhlophe echazwe kakuhle kunye nokusebenza okumangalisayo. Idatha yovavanyo ibonisa ukuba i-whitening pieneng propasses igqitha kwi "Munening Ginering" i-arbutin engaphezulu kwamawakawaka (njengoko kuchaziwe kwidatha yovavanyo).
Abaphandi baqhuba imodeli yovavanyo lwezilwanyana besebenzisa i-zebrafish ukuvavanya isiphumo sokuthintela i-Glabriddi kwi-fizin, etyhila ukuthelekisa okubonakalayo ne-Kojic acid kunye ne-Bhebberry.
Ukongeza kwiimvavanyo zezilwanyana, iziphumo zeklinikhi zikwabonisa imeko ebonakalayo ye-Glabridin, kwiziphumo ezibonakalayo ziqwalaselwe kwiiveki ezi-4.
Ngelixa ukusebenza kwesi sithako esimhlophe kuyabonakala, ukusetyenziswa kwayo akuyongozi njengezinye izithako ezimhlophe. Ngokoluvo lwam, esona sizathu siphambili silele "kwimeko yegolide" kwishishini-ixabisa kakhulu! Nangona kunjalo, emva kokusetyenziswa kweemveliso zesikhumba ngaphezulu, kukho imeko ekhulayo yabantu abafuna iimveliso ezinesithako "seGolden".

I-No.6 Zeziphi iimveliso ze-Skerecare zine-glabridin?

Iphepha elichazayo: Oku kulandelayo luluhlu, hayi ingcebiso!
I-Glabridin yi-Slumcare eNzululwazi eyaziwa ngokuba ziipropathi zayo ezikhanyayo. Inokufumaneka kwiimveliso ezahlukeneyo zolusu, kubandakanya iiSerum, izixhobo, i-Ations kunye nemaski. Ezinye iimveliso ezithile ezinokufumana i-Glabridin, nangona kunjalo, kubalulekile ukuba ubukho be-Glabridin kwiimveliso ze-skercare zingahluka, kwaye kuyacetyiswa ukuba uphonononge uluhlu ngononophelo lweemveliso ezithile zokuchonga ukubandakanywa ngenyameko.
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Uluhlu lwamathanga amathanga "I-Glycyrrrshiza iGlabra" Njengomthamo wesibini (amanzi alandelayo), kunye ne-glyrin, i-sodium, i-sodium ne-squallane, kunye nezinye izinto zokuthambisa.
(2) I-Makeup yabantwana yokukhanya kweziqhamo
Izithako eziphambili zibandakanya i-Glycyrrrshiza i-Glabra ekhutshiweyo, i-Arbutin, i-Arbutin, i-Polygonum Cuspidatum Ingcambu yengcambu, kwaye ngaphezulu.
(3) I-KOSKIN CLOCK WOKUGQIBELA
I-5% i-nitinamide, i-377, kunye ne-glabridin njengezinto zayo eziphambili.
(4) Imaski ye-IITARIDI
Olu luhlu lweemveliso luyahluka, kunye neemali ezincinci kwaye zithengiswe njenge-herbal "glabragan."
(5) I-Gulo Curice Series

No.7 Umphefumlo

(1) Ngaba i-glabridin kwiimveliso ze-skercare zikhutshiwe ngokwenyani kwilayisensi?
Umbuzo wokuba ingaba i-glabridin kwiimveliso ze-skercare zikhutshwe ngokwenyani kwilayisensi) esebenzayo. Isakhiwo sekhemikhali semichiza ekhupha, ngakumbi iGlabridin, icacile, kwaye inkqubo yokukhupha inokubiza kakhulu. Oku kuphakamisa umbuzo wokuba kunokuba luncedo ngakumbi ukuqwalasela i-synthesic synthesis njengenye indlela yokufumana i-glacidin. Ngelixa ezinye iziko, ezinje nge-artemisinin, zinokufumaneka ngokusebenzisa i-synthesis iyonke, kuyinto eyenzekayo yokuqokelela i-glabridin. Nangona kunjalo, iindleko zeendleko zeSynthesic Synthesi xa kuthelekiswa nokukhutshwa kufuneka ziqwalaselwe. Ukongeza, kunokubakho inkxalabo malunga nokusetyenziswa ngabom kwe "Glycyrrrrrthra i-clabra ekhutshiwe" kuluhlu lwemveliso ye-skercare ukwenza isibheno sokuthengisa isithanga sendalo. Kubalulekile ukuba ube nemvelaphi kwimvelaphi kunye neendlela zokuveliswa kwezithako ze-skerecare ukuqinisekisa ukucaca kunye nobunyani.

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Impendulo yinto endenziwa ngayo! Ngelixa isiphumo esimhlophe se-glabriddin siyancomeka, iipropathi zayo zinciphisa isicelo ngqo isicelo. I-Glycyrrhize iphantse ingena emanzini, kwaye amandla ayo okungena kumqobo wesikhumba abuthathaka. Ibandakanya iMveliso ye-SkereCare inyanzelisa imveliso engqongqo kunye neenkqubo zokulungiselela. Ngaphandle kokuqulunqwa okufanelekileyo, kuya kuba ngumceli mngeni ukufezekisa isiphumo esifunayo. Nangona kunjalo, uphando lwenzululwazi lukhokelele ekuphuhlisweni kwamalungiselelo aphezulu e-POSOMS, ukwandisa ukufunxa i-glabriddin ngolusu.

Izalathiso:
[1] Utshintsho: I-DYSCHROMIA [M]. I-Shierry Superron noJean-Paul Ortonne, ka-2010.
[2] J. Chen et al. / I-Specimica Parta Inxalenye A: I-Molecroular kunye ne-biomolecular specturcopy 168 (2016) 111-117