Iindaba - Ngaba iintsana zingatya i-Nervonic Acid?

I. Intshayelelo

Abazali abaninzi bayazibuza ukuba iintsana zingayisebenzisa na i-nervonic acid. Ngaphambi kokuba uphendule lo mbuzo, kubalulekile ukuqonda imithombo ye-nervonic acid. Ekubeni ubisi lwebele lune-nervonic acid, umntu unokubuza ukuba ubisi lwebele alufanelekanga na ukutyiwa. Kodwa ngaphaya kobisi lwebele, ngaba iintsana ezingaphantsi kweminyaka emi-3 ubudala zingayisebenzisa i-nervonic acid evela kwezinye iindawo?

II. Yintoni iNervonic Acid?

I-asidi ye-nervonic, ekwaziwa ngokuba yi-selacholeic acid, ibizwa ngokwesayensi ngokuba yi-cis-15-tetracosenoic acid. Luhlobo lwe-omega-9 monounsaturated fatty acid. Ngenxa yokufunyanwa kwayo kokuqala kwizicubu zemithambo-luvo yezilwanyana ezincancisayo, idla ngokubizwa ngokuba yi-nervonic acid.

I-Nervonic acid yinxalenye yee-membrane zebhayoloji, ngokuyintloko ifumaneka kwimo ye-glycolipids kunye ne-sphingomyelin kwi-white matter yengqondo yomntu, i-retina, isidoda, kunye nezicubu ze-nervous.

III. Iingenelo zeNervonic Acid

Igama elithi "nervonic acid" libonisa umsebenzi wayo oyintloko: ukunceda inkqubo yemithambo-luvo. Ukongeza, ngenxa yokuba ayinamanzi, ikwabonelela ngeenzuzo zentliziyo. Masikhe sijonge nzulu:

Ikhuthaza Uphuhliso Lobuchopho

Ukuthelekiswa kweentsana ezizelwe ngaphambi kwexesha kunye neentsana ezizelwe ngokupheleleyo kubonise amanqanaba aphezulu e-nervonic acid kwiingqondo zeentsana ezizelwe ngokupheleleyo. Izifundo zibonisa ukuba i-nervonic acid inokuba nefuthe ekukhuleni komjikelezo wentloko yeentsana.
I-Nervonic acid ilawula ukusebenza kwe-membrane yeseli yobuchopho, iphucula ukudluliselwa kolwazi phakathi kweeseli zobuchopho kwaye iphucula umsebenzi we-calcium ion. Izifundo zezilwanyana ziyakuxhasa oku, zibonisa ukuba izongezo ze-nervonic acid zomlomo zinokuphucula ukufunda kunye nenkumbulo kwiimpuku eziqhelekileyo kunye nezo ziphazamisekileyo kwimemori. Ke ngoko, kucingelwa ukuba i-nervonic acid inokuphucula inkumbulo kunye nokuqonda komntu.

Iphucula Ukugxila

Ingxaki yokungakhathali (ADHD) ibonakaliswa kukungakhathali, ukungakhathali, kunye nokusebenza kakhulu. I-ADHD inokubangela ukungaphumeleli kwizifundo, ubudlelwane obubi noontanga, kunye nokusebenza kakubi kwentlalo. Izifundo zibonise ukuba abantwana abane-ADHD banamanqanaba aphantsi e-nervonic acid kwi-plasma yabo xa kuthelekiswa nabantwana abaqhelekileyo. Uphando lubonisa ukuba ukongeza izixa ezaneleyo ze-nervonic acid kunokuphucula iimpawu ze-ADHD kunye nokugxila ebantwaneni.

Yehlisa umngcipheko we-Alzheimer's, i-Psychosis, kunye noxinzelelo

Uhlalutyo lwabantu abadala abangama-260 abaneengxaki zokuqonda kunye neeprofayili zabo ze-serum fatty acid lubonise umngcipheko ophantsi wesifo se-Alzheimer's (AD) kunye namanqanaba aphezulu e-nervonic acid kunye ne-DHA. Ukongeza, iimvavanyo zibonise ukuba i-nervonic acid-containing maple seed oil ingenza indlela yokubonisa i-BDNF/TrkB ingasebenzi, inyuse ukubonakaliswa kweeproteni ze-postsynaptic PSD95, GluA1, kunye ne-NMDAR1, kwaye inciphise amanqanaba e-mRNA yezinto ezivuthayo ezifana ne-IL-1β, TNFα, kunye ne-IL-6, ngaloo ndlela inciphisa ubuthathaka be-neurological kunye nokuphucula inkumbulo kubantu abadala.
Ezinye izifundo zidibanise amanqanaba aphantsi e-nervonic acid kwiimpawu ze-prodromal ze-psychosis kunye nokudakumba. Uphando lubonisa ukuba ukongezwa okwaneleyo kwe-nervonic acid kunokunciphisa umngcipheko we-Alzheimer's, i-psychosis, kunye nokudakumba.

Ikhuthaza Ukulungiswa kweMyelin

Uvavanyo olwenziwe kwiimpuku ezine-demyelination ezinikwe ioyile yembewu yemaple equlethe i-nervonic acid lubonise ukuba ezi impuku ziphantse zabuyela kwinqanaba leqela lolawulo. Ezinye izifundo zibonise ukuba ukongezwa kokutya nge-nervonic acid kunokuphucula ukuvuthwa kunye nokubuyiselwa kwe-oligodendrocytes kwi-myelination.

Yehlisa umngcipheko wesifo sentliziyo

Izifundo zifumanise ukuba i-nervonic acid inokunciphisa umngcipheko we-acute ischemic stroke. Izizathu ziquka:
Ukulungisa nokucoca iindlela zemithambo-luvo ezonakeleyo engqondweni
Ukubuyisela umsebenzi weziphelo zemithambo-luvo
Ukukhuthaza ukuvuselelwa kweeseli zemithambo-luvo
Ukuthintela ukuguga kwemithambo-luvo yengqondo
Ukulungisa nokubuyisela iindonga ezigugileyo, ezonakeleyo, neziqinileyo zenkqubo yentliziyo
Ukuhlaziya izicubu zodonga lwemithambo yegazi
Ukubuyisela ukuqina kunye namandla emithambo yegazi

IV. Ngaba iintsana zingayisebenzisa i-Nervonic Acid? Kufuneka ziqale nini ukongeza kwi-supplementation?

Impendulo icacile ngokwenene. Makhe sihlolisise uvavanyo lwamasebe asemthethweni asekhaya nakwamanye amazwe, kunye nemigaqo efanelekileyo yokutya.

1. Imigaqo ye-FDA

Ngokweengxelo ezisemthethweni ze-FDA, i-nervonic acid ephuma kwiikhompawundi ingasetyenziswa njengeyeza.
Ukunyanga izifo ezifana ne-isovaleric acidemia, idosi yi-200-300mg.

Nangona kunjalo, i-FDA ayikayiqinisekisi i-nervonic acid evela kwezinye iindawo ukuba isetyenziswe kwifomula yosana. Ngokwemigaqo ye-FDA, ukuba isithako siza kusetyenziswa kwifomula yosana, kufuneka samkelwe njengeSiqapheleka Jikelele njengeSikhuselekileyo (GRAS) yi-US FDA kwifomula yosana. I-Nervonic acid ngokucacileyo ayihlangabezani nale mfuneko.

2. Imigaqo ye-EU

I-EU ayikayiphononongi ngokuthe ngqo i-nervonic acid, ngoko ke akukho lwazi lufanelekileyo lufumanekayo.

3. Imithetho yaseTshayina

Kwangomhla wama-22 kweyoKwindla ngo-2011, uMphathiswa wezeMpilo wakhupha isaziso esibhengeza ukuba ioyile yembewu yemaple ipasisile isaziso esitsha sokutya kwezixhobo.

Ukudibanisa imithetho kunye nokubuza umxholo we-nervonic acid kwioyile yembewu yemaple, kufunyaniswe ukuba ioyile yembewu yemaple idla ngokuba ne-nervonic acid eyi-3%-5%. Ngokwemithetho emitsha yokutya okunezixhobo, umda wokutya kwe-nervonic acid imihla ngemihla umalunga ne-150mg.
Njengoko bekutshiwo ngaphambili, igama lekhemikhali le-nervonic acid yi-cis-15-tetracosenoic acid. Ngo-2017, iKhomishini yeSizwe yezeMpilo kunye noCwangciso lweNtsapho ikhuphe esinye isaziso esitsha sokutya okunezixhobo malunga neekhompawundi ze-nervonic acid ezivela kwioyile yerapeseed.

Esi sibhengezo sigxininise ngokukodwa ukuba iintsana akufuneki zitye ezo mveliso, kwaye ukuba imveliso isebenzisa ngqo le mveliso, ilebheli kufuneka ibonise ukuba ayifanelekanga kwiintsana.

Ngokusekelwe kwimigaqo ekhoyo ngoku, nokuba i-nervonic acid ifumaneka kwiikhompawundi okanye kwimithombo yokutya, ayifanelekanga kwiintsana. Abantu abaninzi banokubuza, "Kodwa ukuba ubisi lwebele lunayo, kutheni singayisebenzisi?" Oku kubandakanya iinkalo ezimbini. Okokuqala, okwangoku kukho uphando olulinganiselweyo malunga nokhuseleko lwe-nervonic acid kwiintsana, kwaye ayikasetyenziswa kakhulu kwihlabathi liphela. Kufuneka uphando olongezelelweyo. Okwesibini, ukuba iintsana kufuneka zongeze i-nervonic acid na ngumbuzo ongenalo uphando oloneleyo. Okwangoku akukho datha ibalulekileyo yokubonisa ukuba iintsana azinayo i-nervonic acid eyaneleyo. Ke ngoko, kufuneka uphando olongezelelweyo ukuqinisekisa oku.

Ngoko ke, ngokusekelwe kwimigaqo kunye novavanyo lwangoku, kuyacetyiswa ukuba uqalise ukongeza i-nervonic acid xa uneminyaka emi-3 nangaphezulu. Abazali abaninzi banokuziva bekhululekile ukuba bongeza iintsana ezingaphantsi kweminyaka emi-3 ubudala. Kwiimeko ezinjalo, kucetyiswa ukongezwa kokutya.

Ukuphinda ndithi, akukho bungqina baneleyo obuxhasa ukongezwa kwe-nervonic acid kwiintsana. Ngokwembono yezonyango neyokutya, akukho datha ebonisa ukuba ukongezwa kuyimfuneko. Ke ngoko, kuyacetyiswa ukuba kuthathwe indlela enengqondo yokongeza i-nervonic acid kwiintsana.

Nangona wonke umzali enethemba lokufumana umntwana okrelekrele, kuyacetyiswa ukuba ugxile kwisondlo ngelixa uchitha ixesha elingakumbi nomntwana wakho, ukubonelela ngendawo yokuhlala esempilweni, kwaye ukhuthaze imisebenzi yangaphandle. Ezi zinto zihlala zibaluleke ngakumbi.