Cycloastragenolyikhompawundi yendalo eye yafumana ingqwalasela kwiminyaka yakutshanje ngenxa yeenzuzo zayo zempilo ezinokubakhona. Yi-saponin ye-triterpenoid efumaneka kwiingcambu ze-Astragalus membranaceus, imifuno yendabuko yaseTshayina. Le khompawundi ibingumxholo wezifundo ezininzi ngenxa yengxelo yayo yokuchasa ukuguga, i-anti-inflammatory, kunye ne-immune-modulating properties. Kweli nqaku, siza kuphonononga imithombo ye-cycloastragenol kunye neenzuzo zayo zempilo ezinokubakho.
Imithombo yeCycloastragenol
I-Astragalus membranaceus: Owona mthombo wendalo we-cycloastragenol yingcambu ye-Astragalus membranaceus, ekwabizwa ngokuba yi-Huang Qi kumayeza emveli aseTshayina. Lo mchiza usetyenziswe kangangeenkulungwane kumayeza emveli aseTshayina kwiipropathi zawo ezahlukeneyo zokukhuthaza impilo. Iingcambu ze-Astragalus membranaceus ziqulethe i-cycloastragenol, kunye nezinye iikhompawundi ze-bioactive ezifana ne-astragaloside IV, i-polysaccharides, kunye ne-flavonoids.
Izongezelelo: I-Cycloastragenol iyafumaneka kwifomu yokongeza. Ezi zongezelelo ziqhele ukuvela kwingcambu ye-Astragalus membranaceus kwaye zithengiswa ngenxa yeziphumo zazo zokuchasa ukuguga kunye nefuthe lokuqinisa umzimba. Kubalulekile ukuqaphela ukuba umgangatho kunye nokucoceka kwezongezelelo ze-cycloastragenol zinokwahluka, ngoko ke kubalulekile ukukhetha iimveliso ezivela kubavelisi abahloniphekileyo.
IiNzuzo zeMpilo zeCycloastragenol
Iipropathi zokuchasa ukuguga: Enye yezona zinto zifundiswa ngokubanzi iingenelo ezinokubakho ze-cycloastragenol ziziphumo zayo zokuchasa ukuguga. Uphando lubonisa ukuba i-cycloastragenol inokuthi isebenze i-telomerase, i-enzyme edlala indima ebalulekileyo ekugcineni ubude be-telomeres, i-caps ekhuselayo ekupheleni kwe-chromosomes. Ii-telomeres ezimfutshane zinxulunyaniswa nokuguga kunye nezifo ezinxulumene neminyaka, kwaye ukusebenza kwe-telomerase nge-cycloastragenol kunokunceda ukukhusela ngokuchasene nokuguga kweselula.
Iimpembelelo ezichasayo: I-Cycloastragenol ibonakaliswe ukuba inezixhobo ezichasayo, ezinokuba luncedo ekulawuleni iimeko ezahlukeneyo zokuvuvukala. Ukudumba yimpendulo yendalo yamajoni omzimba, kodwa ukudumba okungapheliyo kunxulunyaniswa noluhlu lwemiba yezempilo, kubandakanya isifo sentliziyo, isifo samathambo, kunye nokuphazamiseka kwemithambo-luvo. Ngokunciphisa ukuvuvukala, i-cycloastragenol inokunceda ukuxhasa impilo yonke kunye nokuphila kakuhle.
Ukumodareyitha amajoni omzimba: Uphononongo lubonise ukuba i-cycloastragenol inokulungelelanisa amajoni omzimba, iphucula amandla ayo okuzikhusela kusulelo kunye nezifo. Esi siphumo sokuguqula umzimba sinokuba luncedo ngakumbi kubantu abanokusebenza komzimba okubuthathaka okanye abo bafuna ukuxhasa amajoni abo omzimba ngexesha loxinzelelo okanye ukugula.
Ukuqukumbela, i-cycloastragenol yikhompawundi yendalo efumaneka kwingcambu ye-Astragalus membranaceus, kwaye iyafumaneka nakwifomu yokongeza. Uphando lucebisa ukuba i-cycloastragenol inokubonelela ngezibonelelo zempilo ezinokubakho, kubandakanya ukulwa nokuguga, ukuchasana nokudumba, kunye neziphumo zokumodareyitha amajoni omzimba. Nangona kunjalo, uphando olongezelelweyo luyafuneka ukuze kuqondwe ngokupheleleyo iindlela zayo zokwenza kunye nemiphumo yayo yexesha elide kwimpilo yabantu. Njengaso nasiphi na isongezelelo, kubalulekile ukudibana nengcali yezempilo ngaphambi kokusebenzisa i-cycloastragenol, ngakumbi ukuba unayo nayiphi na imeko yezempilo ephantsi okanye uthatha amayeza.
Ngaba i-cycloastragenol ikhuselekile?
Ukhuseleko lwe-cycloastragenol lube ngumxholo wengxoxo phakathi kwabaphandi kunye nabasebenzi bezempilo. Nangona uphando oluthile lucebise ukuba lunokuba neenzuzo zempilo, kukho uphando oluncinci malunga nokhuseleko lwexesha elide kunye neziphumo ebezingalindelekanga. Ngenxa yoko, kubalulekile ukujongana nokusetyenziswa kwe-cycloastragenol ngononophelo kwaye udibane nengcali yezempilo ngaphambi kokuba uyifake kwindlela yakho yokuphila kakuhle.
Imingcipheko enokubakho kunye neziphumo ebezingalindelekanga ze-cycloastragenol
Ngelixa i-cycloastragenol inokubonelela ngezibonelelo zempilo ezinokubakho, kukwakho iinkxalabo malunga nokhuseleko lwayo kunye neziphumo ebezingalindelekanga. Uphando oluncinci luye lwenziwa kukhuseleko lwexesha elide lwe-cycloastragenol, kwaye ngenxa yoko, kukho ukungabikho kolwazi malunga neengozi zayo kunye nemiphumo emibi.
Abanye abantu banokuba neziphumo ebezingalindelekanga ezingephi xa bethatha i-cycloastragenol, njengokungakhululeki kokwetyisa okanye ukuchasana nokungalungi. Ukongeza, ngenxa yokuba i-cycloastragenol ibonakaliswe ukuba imodareyitha amajoni omzimba, kukho inkxalabo yokuba inokuba namandla okwandisa iimeko ezithile zokuzikhusela komzimba okanye iphazamise amayeza acinezela umzimba.
Kwakhona kubalulekile ukuqaphela ukuba umgangatho kunye nokucoceka kwezongezelelo ze-cycloastragenol zinokwahluka, kwaye kukho umngcipheko wokungcola okanye ukuphinga. Ngenxa yoko, kubalulekile ukukhetha umthombo othembekileyo nothembekileyo xa kuthengwa izongezo ze-cycloastragenol.
Iingcamango zokugqibela
Ukuqukumbela, ngelixa i-cycloastragenol ibonisa isithembiso sezempilo ezinokubakho, kukho uphando olulinganiselweyo malunga nokhuseleko lwexesha elide kunye neziphumo ebezingalindelekanga ezinokwenzeka. Ngenxa yoko, kubalulekile ukujongana nokusetyenziswa kwe-cycloastragenol ngononophelo kwaye udibane nengcali yezempilo ngaphambi kokuba uyifake kwindlela yakho yokuphila kakuhle. Ukongeza, kubalulekile ukukhetha isongezelelo somgangatho ophezulu ukusuka kumthombo othembekileyo ukunciphisa umngcipheko wongcoliseko okanye ukukrexeza. Uphando oluthe kratya luyafuneka ukuze kuqondwe ngokupheleleyo ukhuseleko kunye nokusebenza ngempumelelo kwe-cycloastragenol, kwaye okwangoku, abantu kufuneka balumke xa bejonga ukusetyenziswa kwayo.
IiReferensi:
1. Lee Y, Kim H, Kim S, et al. I-Cycloastragenol yinto enamandla ye-telomerase activator kwiiseli ze-neuronal: iimpembelelo kulawulo lokudakumba. Neuroreport. 2018;29(3):183-189.
2. Wang Z, Li J, Wang Y, et al. I-Cycloastragenol, i-triterpenoid saponin, iphucula uphuhliso lovavanyo lwe-autoimmune encephalomyelitis ngokucinezelwa kwe-neuroinflammation kunye ne-neurodegeneration. Biochem Pharmacol. 2019;163:321-335.
3. ULiu P, uZhao H, uLuo Y. Imiphumo yokuchasana nokuvuvukala kwe-cycloastragenol kwimodeli yemouse ye-LPS-induced mastitis. Ukudumba. 2019;42(6):2093-2102.
Ixesha lokuposa: Apr-19-2024