Ziziphi iiNzuzo zeMpilo zeNqolowa yeNkomfa yeSpermidine?

Iziphumo zokuchasa ukuguga:I-Spermidine iye yadibaniswa nemiphumo yokuchasana nokuguga, njengoko ibandakanyeka kulawulo lwe-autophagy, inkqubo yeselula enceda ukususa amacandelo eeseli ezonakalisiweyo kunye nokukhuthaza impilo yeselula. Le nkqubo ihambelana nokucocwa kwee-organelles ezonakalisiweyo kunye neeprotheyini ezidibeneyo, ezinokuthi ziqokelele ngobudala kwaye zibe negalelo kwizifo ezahlukahlukeneyo. Ngokukhuthaza i-autophagy, i-spermidine inokunceda ukugcina impilo yeselula kunye nokusebenza, okunokwandisa ixesha lokuphila kweeseli kunye nokulibazisa ukuqala kwezifo ezinxulumene neminyaka.

Impilo yentliziyo:I-Spermidine ibonise amandla okuphucula impilo ye-cardiovascular. Ifunyaniswe ukunciphisa uphuhliso lwe-atherosclerosis ngokunciphisa ukuvuvukala kunye nokuphucula ukusebenza kweseli (mitochondria). Ukongezelela, i-spermidine inokunciphisa ukubunjwa kwe-blood clot (i-platelet aggregation) kwaye iphucule umphumo oqhelekileyo wokuhlanjululwa kweeseli ezidibanisa imithwalo yegazi, igalelo ekunciphiseni uxinzelelo lwegazi kunye nokuthintela ukungaphumeleli kwentliziyo.

Ukhuseleko lweNeuro:I-Spermidine inokukhusela ukonakaliswa kwemithambo-luvo engqondweni, inokuthintela izifo ze-neurologic ezifana ne-Alzheimer's kunye ne-Parkinson. Kuye kwaboniswa ukunceda ukunciphisa ingqiqo, imemori, kunye nokukhubazeka okusebenzayo okuhambelana nokuguga.

Ummiselo weswekile yegazi:I-Spermidine ibonakaliswe ukuphucula amandla omzimba okusebenzisa i-insulin kunye nokunciphisa amanqanaba eswekile yegazi, enokuba luncedo ekulawuleni isifo seswekile.

Impilo Yamathambo:I-Spermidine inokwandisa amandla ethambo kwaye ithintele ukulahleka kwethambo, okwenza kube luncedo ekuthinteleni i-osteoporosis. Iyakwazi nokuthintela ukulahleka okunxulumene neminyaka ye-muscle ye-skeletal kunye nokuphucula ukusebenza kwemisipha.

Inkxaso yesixokelelwano samajoni omzimba:I-Spermidine ibonise iipropathi ezichasayo kwaye inokunceda ekunciphiseni ubunzima besifo sesibindi esivuthayo. Kwakhona kubonakaliswe ukuphucula umsebenzi weeseli zomzimba ezivela kubaxhasi babantu abadala kunye nokunciphisa ukwanda kwentsholongwane, ebonisa indima ekomelezeni amajoni omzimba ngokuchasene nezoyikiso zangaphandle.

Iziphumo ze-Epigenetic:I-Spermidine inokuchaphazela i-epigenetic landscape ngokunciphisa i-histone acetylation kunye nokuchaphazela imeko ye-acetylation yeeprotheni ezininzi ze-cytoplasmic. Oku kunokuchaphazela ukubonakaliswa kofuzo kunye neenkqubo zeselula, kuquka i-autophagy.

Umsebenzi weMitochondrial:I-Spermidine inxulunyaniswe nomsebenzi ophuculweyo we-mitochondrial, obalulekileyo kwimveliso yamandla ngaphakathi kweeseli. Inokukhuthaza ukuveliswa kwe-mitochondria entsha kunye nokuphucula ukucaciswa kwezonakalisiweyo ngenkqubo ebizwa ngokuba yi-mitophagy.

Ukuqukumbela, i-wheat germ extract i-spermidine inika uluhlu lweenzuzo zempilo ezinokubakho, ukusuka kwimiphumo yokuchasana nokuguga ukuxhasa umsebenzi wokuqonda, impilo ye-cardiovascular, kunye nenkxaso ye-immune system. Nangona kunjalo, kubalulekile ukuqaphela ukuba ngelixa i-spermidine iyinxalenye yendalo efumaneka kukutya okuninzi kwaye ixhatshazwa kakuhle, kusoloko kucetyiswa ukuba udibane nochwepheshe bezempilo ngaphambi kokuba wenze utshintsho olubalulekileyo kwisondlo sakho okanye kwirejimeni yokuncedisa.